Results 41 to 50 of about 165,720 (231)

Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden. [PDF]

PLoS ONE, 2010
Fas, a member of the tumor necrosis family, is responsible for initiating the apoptotic pathway when bound to its ligand, Fas-L. Defects in the Fas-mediated apoptotic pathway have been reported in colorectal cancer.In the present study, a variant of the ...
Hector Guillen-Ahlers, Mark A Suckow, Francis J Castellino, Victoria A Ploplis   +3 more
doaj   +1 more source

Updating the fatty acid profiles of retail bovine milk in China based on an improved GC-MS method: implications for nutrition

Frontiers in Nutrition, 2023
The importance of food components to potential benefits and risks to human health is gradually being consumer awareness. Milk is an important part of the lipid content of the human diet, and there are few detailed reports on the fatty acid (FA) profiles ...
Meiqing Chen, Meiqing Chen, Fengen Wang, Xufang Wu, Xufang Wu, Boxue Si, Boxue Si, Junyu Pan, Junyu Pan, Nan Zheng, Nan Zheng, Yangdong Zhang, Yangdong Zhang, Jiaqi Wang, Jiaqi Wang   +14 more
doaj   +1 more source

Chico Bastidores: Na voz dos fãs [PDF]

, 2017
Este artigo analisa a estratégia de marketing online desenvolvida para o lançamento de Chico, o novo CD do cantor e compositor brasileiro Chico Buarque de Holanda e a adesão dos fãs ao projeto na Internet.
Filho, G.
core  

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Outing midiático no voleibol: performance, voleifãs e paradoxos da visibilidade lésbica

Revista Estudos Feministas
O presente estudo parte do episódio midiático de um beijo entre duas atletas de vôlei como instaurador de performances em redes sociais digitais que envolvem: as especulações sobre a sexualidade de atletas lésbicas em ambientes digitais como traço ...
Cecília Almeida Rodrigues Lima, Thiago Soares   +1 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

The Cumulative Incidence and Risk Factors of Recurrent Venous Thromboembolism in the Elderly

Vascular Health and Risk Management, 2020
Fahad AS Aleidan1,2 1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 2Anticoagulation Clinic, King Abdulaziz Medical City, Riyadh, Saudi ArabiaCorrespondence: Fahad AS AleidanCollege of Medicine, King ...
Aleidan FAS
doaj  

AS PRÁTICAS DA CULTURA DE FÃS COMO IMPULSIONADORAS DA INDÚSTRIA CRIATIVA

, 2023
Os fãs, a partir da cultura de fãs, transformam as dinâmicas de produção, distribuição e consumo de mídia. A partir da revisão da literatura (LAVILLE; DIONE, 1999) dos Estudos Culturais (CANCLINI, 2015; ESCOSTEGUY, 2006; GROSSBERG, 1992) e das teorias da
Ribeiro Cardoso, Julianny, Cardoso, Julianny, Nolibos Baccin, Alciane   +2 more
core  

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source