Results 61 to 70 of about 173,176 (244)

Beyond photoaging: additional factors involved in the process of skin aging

Clinical, Cosmetic and Investigational Dermatology, 2018
Flavia Alvim Sant’Anna Addor MEDCIN Research, Private Clinical Research Center, Osasco, São Paulo, Brazil Abstract: Studies assessing the impact of extrinsic factors on skin aging have increased during the last with the increase in life ...
Addor FAS
doaj  

The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins

BMC Neuroscience, 2004
Background Apoptosis is important for normal cerebral cortical development. We previously showed that the Fas suicide receptor was expressed within the developing cerebral cortex, and that in vitro Fas activation resulted in caspase-dependent death ...
Newman Joseph M, Wade Stephen B, Santillano Daniel R, Cheema Zulfiqar F, Miranda Rajesh C   +4 more
doaj   +1 more source

Childish Gambino y la serie "Atlanta": el uso de Internet para una experiencia inmersiva [PDF]

, 2018
O seguinte artigo tem o intuito de analisar a série estadunidense Atlanta, mais especificamente as estratégias transmidiáticas que seu criador, Donald Glover, utiliza para ampliar o universo narrativo da série, assim como a influência do conceito de ...
Hygino, Lincoln André Bolzon
core  

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Ficção televisiva brasileira e fãs online: mapeamentos e investigações

Comunicação & Educação, 2016
O presente texto apresenta uma síntese da obra Por uma teoria de fãs da ficção televisiva brasileira[1], resultado de dez pesquisas colaborativas desenvolvidas entre 2014 e 2015 pela equipe de investigadores da rede Obitel Brasil.
Lucas Martins Néia
doaj  

Escrever para Cinema [PDF]

, 2008
Obra centrada na especificidade da escrita de um argumento para ...
Sobral, Filomena Antunes
core  

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers.

PLoS Biology, 2016
Demonstrations of both pro-apoptotic and pro-survival abilities of Fas (TNFRSF6/CD95/APO-1) have led to a shift from the exclusive "Fas apoptosis" to "Fas multisignals" paradigm and the acceptance that Fas-related therapies face a major challenge, as it ...
Krittalak Chakrabandhu, Sébastien Huault, Jérôme Durivault, Kévin Lang, Ly Ta Ngoc, Angelique Bole, Eszter Doma, Benoit Dérijard, Jean-Pierre Gérard, Michel Pierres, Anne-Odile Hueber   +10 more
doaj   +1 more source

Escrever para Cinema Etapas da Criação de um Argumento [PDF]

, 2008
Dinâmico e de fácil leitura, Escrever Para Cinema - Etapas da Criação de um Argumento é um must see para argumentistas, realizadores, estudantes ou meros fãs de cinema.
Sobral, Filomena Antunes
core  

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source