Results 81 to 90 of about 179,884 (241)

Análise dos fatores associados a quedas com fratura de fêmur em idosos: um estudo caso-controle [PDF]

, 2015
OBJETIVO: Identificar os principais fatores associados a quedas e fraturas de fêmur em idosos. MÉTODOS: Trata-se de estudo caso-controle (um grupo de casos e dois grupos controle) na proporção de 1:1:1, em que foram estudados 135 indivíduos com idade ≥60
Soares,Danilo Simoni, Silva,Anderson Soares da, Mello,Luane Marques de, Nunes,Altacílio Aparecido   +3 more
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Fasciíte necrosante pós-osteossíntese de fratura transtrocantérica do fêmur

Revista Brasileira de Ortopedia, 2014
A fasciíte necrosante é uma rara e potencialmente letal infecção de partes moles. A seguir, descreveremos o caso de uma paciente portadora de fratura transtrocantérica do fêmur que evoluiu com fasciíte necrosante após a osteossíntese da fratura.
Leandro Emílio Nascimento Santos, Robinson Esteves Santos Pires, Leonardo Brandão Figueiredo, Eduardo Augusto Marques Soares   +3 more
doaj   +1 more source

Sobrevida de idosos hospitalizados em terapia intensiva por fratura de fêmur

, 2022
Introdução: Em idosos com fratura de fêmur, a internação em Unidade de Tratamento Intensivo (UTI) ocorre, na grande maioria dos casos, relacionado ao tratamento que pode envolver cirurgia de grande porte, e ainda pelo fato de apresentarem instabilidade ...
Rodrigues, Marcela Bongiovani [UNIFESP]
core  

Transposição do enxerto vascularizado da fíbula pro fêmur diafisário sem microanastomoses [PDF]

, 2010
OBJETIVO: O estudo descreve uma maneira nova e simples de transplantar o enxerto ósseo vascularizado da fíbula pro fêmur diafisário sem necessidade de microcirurgia, demonstra o caso clínico operado com bom resultado quanto a vascularização e ...
Fabiano Inácio de Souza, Guilherme Pelosini Gaiarsa, Hsiang Wei Teng, Luciano Ruiz Torres, Francisco Perez Soro Neto, Fernanda Bogdanovics Paganotti, Dan Carai Maia Viola, Rames Mattar Júnior, Clécio Seiji Yuhara, Leonardo Franco Pinheiro Gaia   +9 more
core   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Lag Vidasının Farklı Sabitleme Pozisyonunda, Dinamik Kalça Çivisi ile Tedavi Edilen İntertrokanterik Femoral Kırıklarının Kararlılığı

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2013
Bu çalışmada, Dinamik Kalça Çivisinin (DKÇ) sabitlenmesinde lag vidasının farklı konumlarına göre intertrokanterik femur kırıklarının kararlılığı analitik olarak incelenmektedir. Bilgisayarlı tomografi görüntüleri kullanılarak oluşturulan insan femurunun
Arif Özkan, İbrahim Mutlu, Talip Çelik, Yasin Kişioğlu   +3 more
doaj   +4 more sources

Single-stage bilateral distal femur replacement for traumatic distal femur fractures

Arthroplasty Today, 2019
Treatment of periprosthetic distal femur fractures and comminuted intraarticular distal femur fractures with previous arthritis remains a difficult challenge for orthopedic surgeons. Previous case series have shown that distal femur replacement (DFR) can
David C. Neal, MD, Varun Sambhariya, MD, Apollo Tran, BS, Shawn K. Rahman, BSA, Thad J. Dean, DO, Russel A. Wagner, MD, Hugo B. Sanchez, MD, PhD   +6 more
doaj   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source