Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17 [PDF]
iScience, 2020 Summary: Membrane curvature has emerged as an intriguing physical principle underlying biological signaling and membrane trafficking. The CIP4/FBP17/Toca-1 F-BAR subfamily is unique in the BAR family because its structurally folded F-BAR domain does not ...
Maohan Su +6 more
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General one-loop formulas for $$H\rightarrow f\bar{f}\gamma $$ H → f f ¯ γ and its applications [PDF]
European Physical Journal C: Particles and Fields, 2022 General one-loop contributions to the decay processes $$H\rightarrow f\bar{f}\gamma $$ H → f f ¯ γ and its applications are presented in this paper. We consider all possible contributions of the additional heavy vector gauge bosons, heavy fermions, and ...
Vo Van On +3 more
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DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division. [PDF]
Mol Biol Cell, 2020 In many organisms, positive and negative signals cooperate to position the division site for cytokinesis. In the rod-shaped fission yeast Schizosaccharomyces pombe, symmetric division is achieved through anillin/Mid1-dependent positive cues released from
Bhattacharjee R +9 more
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The F-BAR Domain of Rga7 Relies on a Cooperative Mechanism of Membrane Binding with a Partner Protein during Fission Yeast Cytokinesis [PDF]
Cell Reports, 2019 Summary: F-BAR proteins bind the plasma membrane (PM) to scaffold and organize the actin cytoskeleton. To understand how F-BAR proteins achieve their PM association, we studied the localization of a Schizosaccharomyces pombe F-BAR protein Rga7, which ...
Yajun Liu +4 more
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The state of F-BAR domains as membrane-bound oligomeric platforms. [PDF]
Trends Cell Biol, 2021 Fes/Cip4 homology Bin/amphiphysin/Rvs (F-BAR) domains, like all BAR domains, are dimeric units that oligomerize and bind membranes. F-BAR domains are generally coupled to additional domains that function in protein binding or have enzymatic activity.
Snider CE +4 more
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Curvature induction and sensing of the F-BAR protein Pacsin1 on lipid membranes via molecular dynamics simulations. [PDF]
Sci Rep, 2019 F-Bin/Amphiphysin/Rvs (F-BAR) domain proteins play essential roles in biological processes that involve membrane remodelling, such as endocytosis and exocytosis. It has been shown that such proteins transform the lipid membrane into tubes.
Mahmood MI, Noguchi H, Okazaki KI.
europepmc +2 more sources
Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. [PDF]
Nat Commun, 2019 The intracellular ciliogenesis pathway requires membrane trafficking, fusion, and reorganization. Here, we demonstrate in human cells and zebrafish that the F-BAR domain containing proteins PACSIN1 and -2 play an essential role in ciliogenesis, similar ...
Insinna C +10 more
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Opposing functions of F-BAR proteins in neuronal membrane protrusion, tubule formation, and neurite outgrowth. [PDF]
Life Sci Alliance, 2019 Neurite formation is a fundamental antecedent to axon and dendrite formation, but the mechanisms that underlie this important process are poorly characterized. Here, we demonstrate that two F-BAR proteins, CIP4 and FBP17, have opposing functions in early
Taylor KL +7 more
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The intrinsically disordered region of the cytokinetic F-BAR protein Cdc15 performs a unique essential function in maintenance of cytokinetic ring integrity. [PDF]
Mol Biol Cell, 2019 Successful separation of two daughter cells (i.e., cytokinesis) is essential for life. Many eukaryotic cells divide using a contractile apparatus called the cytokinetic ring (CR) that associates dynamically with the plasma membrane (PM) and generates ...
Mangione MC, Snider CE, Gould KL.
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The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis [PDF]
Cell Reports, 2016 F-BAR proteins link cellular membranes to the actin cytoskeleton in many biological processes. Here we investigated the function of the Schizosaccharomyces pombe Imp2 F-BAR domain in cytokinesis and find that it is critical for Imp2’s role in contractile
Nathan A. McDonald +6 more
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