Results 211 to 220 of about 216,912 (262)

Mitogenomic analyses uncover significant genetic differentiation between different geographic populations of <i>Acrossocheilus fasciatus</i>. [PDF]

Mitochondrial DNA B Resour
Yuan Y, Zhang H, Jiang S, Yang X, Chung-Davidson YW, Li W, Li J, Li F, Ren J.   +8 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Generalized Legendre Transforms Have Roots in Information Geometry. [PDF]

Entropy (Basel)
Nielsen F.
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Host-driven evolution shapes the polysaccharide utilization profiles of alga-associated Flavobacteriaceae. [PDF]

Microbiome
Cai G, Wu Y, Chen Z, Yang X, Jiang X, Wang Q, Cai R, Wang H.   +7 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Molecular basis for the biosynthetic divergence of anthracyclines kosinostatin and chartreusin. [PDF]

Chem Sci
Fang LL, Jia CH, Zhou X, Ma JY, Guo HZ, Ma X, Bai W, Xiang L, Zhu J, Tan RX, Wang YS.   +10 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Discovering and protecting cryptic biodiversity: A case study of a previously undescribed, vulnerable bird species in Japan. [PDF]

PNAS Nexus
Saitoh T, Shipilina D, Xia C, Zhang L, Seki SI, Olsson U, Alström P.   +6 more
europepmc   +1 more source