Results 111 to 120 of about 52,660 (305)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Rare Earth Dopant (Nd, Gd, Dy, and Er) Hybridization in Lithium Tetraborate

Frontiers in Physics, 2014
The four dopants (Nd, Gd, Dy, and Er) substitutionally occupy the Li+ sites in lithium tetraborate (Li2B4O7: RE) glasses as determined by analysis of the extended X-ray absorption fine structure. The dopants are coordinated by 6-8 oxygen at a distance of
Tony D. Kelly, James C. Petrosky, John W. McClory, Volodymyr T. Adamiv, Yaroslav V. Burak, Bohdan V. Padlyak, Bohdan V. Padlyak, Ihor M. Teslyuk, Ning eLu, Lu eWang, Wai-Ning eMei, Peter A Dowben   +11 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Aeroradiospectrometry in the spatial formation characterization of Ogun State, south-western, Nigeria

Scientific African, 2019
In this study, aeroradiospectrometric data sets of Ogun State, Latitudes (6.2° to 7.8° N) and Longitudes (3.0° to 5.0° E), Nigeria were analyzed for lithological characterization.
F.O. Ogunsanwo, J.A. Olowofela, I.C. Okeyode, O.A. Idowu, O.T. Olurin   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Gamalnorsk *mǫð f. ‘slåtteeng’ i norske stadnamn

Namn og Nemne
Danish and Swedish mad(e) m. ‘flood-meadow’ (cognate of e.g., German Matte and English meadow) presupposes PN *madu and ON *mǫð f., but such a common noun is unattested. Nonetheless, a few Norwegian oeconyms are interpreted as developments of *mǫð f.
Samuele Mascetti
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

On Prediction of Permeability in Sedimentary Rocks Using Geoelectrical Parameters

Water Resources Research
Permeability prediction from geoelectrical measurements on sedimentary rocks remains a longstanding challenge due to the complex interplay between pore structure and electrical properties. This study investigates the relationship between permeability and
Andreas Weller, Klaudio Peshtani, Lee Slater   +2 more
doaj   +1 more source

The lunar nomenclature: The reverse side of the moon (1961-1973) [PDF]

The history of naming the details of the relief on the near and reverse sides of the moon is examined. The book contains lists of the names of craters of the reverse side of the moon in Russian and the Latin ...
Burba, G., Shingareva, K.
core   +1 more source