Results 101 to 110 of about 52,660 (305)

Socjalistyczny w formie, narodowy w treści. Chorwacka odmiana komunistycznej nowomowy w czasie tzw. chorwackiej wiosny

open access: yesStylistyka, 2020
In this article the problem o f Yugoslav Newspeak, in the Croatian version that appeared in the period o f the so-called Croatian Spring (1971), is taken into consideration.
Maciej Czerwiński
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

PCDD/F Formation in Milled Fly Ash: Metal Chloride Catalysis

open access: yesAerosol and Air Quality Research, 2017
ABSTRACTMechanochemical treatment reduces the particle size of fly ash and disperses catalytic metals, raising the potential reactivity of fly ash to form and destroy ‘dioxins’, i.e., polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD + PCDF or PCDD/F).
Ishrat Mubeen   +6 more
openaire   +1 more source

Reparative Spheroids in HPV-Associated Chronic Cervicitis [PDF]

open access: yes, 2013
Background: Spheroid cell structures (SCS) described in cell culture are used to study cell-cell and cell-matrix interactions. However, the role of the SCS in the repair process in vivo remains unexplored. The aim of the study was to examine the cellular
Evgeniya A. Kogan   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Tracing potential sources of hazardous contaminants, Fluoride, Nitrate, and Uranium, using an extended PCA-PMF statistical approach for the Semi-Arid Eastern Plains of Rajasthan, India

open access: yesCleaner Water
This study evaluated groundwater quality and identified possible sources of major ions and trace elements, including Fluoride (F-) and Uranium (U) ions in the Semi-Arid Eastern Plains of Rajasthan.
Vipin Garg   +3 more
doaj   +1 more source

A quantum chemical analysis of Zn and Sb doping and co-doping in SnO2

open access: yesAIP Advances, 2017
This work presents a quantum chemical study of Zn and Sb doping and co-doping in SnO2 carried out by a DFT+U method. The analysis has been developed by introducing three different modifications in the otherwise pure SnO2 system.
Luis Villamagua   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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