Results 91 to 100 of about 52,660 (305)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Development of a high-density lead acetate-monoethylene glycol completion fluid for HPHT reservoirs

open access: yesResults in Engineering
Well completion fluids are vital for hydrocarbon extraction and well integrity, particularly in high-pressure, high-temperature (HPHT) reservoirs. Conventional calcium bromide brines, though dense, face economic and logistical challenges in Iran due to ...
Ali Naghipour   +2 more
doaj   +1 more source

Designing mobile experiences for collocated interaction [PDF]

open access: yes, 2015
Many of our everyday social interactions involve mobile devices. Yet, these tend to only provide good support for distributed social interactions. Although much HCI and CSCW research has explored how we might support collocated, face-to-face situations ...
Fischer, Joel   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Correction: F-Formation Detection: Individuating Free-Standing Conversational Groups in Images

open access: yesPLOS ONE, 2015
There is an error in the first sentence of the Evaluation Metrics subsection of the Experiments section. The correct sentence is: As accuracy measures, we adopt the metrics proposed in [3] and extended in [12]: we consider a group as correctly estimated if at least ⌈(T ⋅ ∣G∣)⌉ of their members are found by the grouping method and correctly detected by ...
Francesco Setti   +4 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analysis of interaction and co-editing patterns amongst OpenStreetMap contributors [PDF]

open access: yes, 2013
OpenStreetMap (OSM) is a very well known and popular Volunteered Geographic Information (VGI) project on the Internet. In January 2013 OSM gained its one millionth registered member.
Corcoran, Padraig, Mooney, Peter
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Track initialisation for multiple formations based on neutrosophic Hough transform

open access: yesIET Radar, Sonar & Navigation
Track crossing is a major issue in the initialisation of multiple‐flight trajectories. To solve this problem, the authors propose a track initialisation algorithm.
Yang Penggang, Wang Kun, Feng Guangdong
doaj   +1 more source

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