Results 91 to 100 of about 12,077,058 (321)
We show that the past and future of half-plane Brownian motion at certain cutpoints are independent of each other after a conformal transformation. Like in Ito's excursion theory, the pieces between cutpoints form a Poisson process with respect to a ...
Virag, Balint
core +4 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Wavefield separation using the f–ξ domain for vertical seismic profiling data [PDF]
Wavefield separation is an essential and critical step in data processing of vertical seismic profiles (VSPs). The τ–p transform is one of the effective approaches for separating the VSP wavefield.
Liu Baotong +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The second continuous Jacobi transform
This paper continues the work started in [1]; a second continuous Jacobi transform is defined for suitable functions f(x). Properties of the transform are studied.
E. Y. Deeba, E. L. Koh
doaj +1 more source
A method for solving nonlinear Volterra’s population growth model of noninteger order
Many numerical methods have been developed for nonlinear fractional integro-differential Volterra’s population model (FVPG). In these methods, to approximate a function on a particular interval, only a restricted number of points have been employed.
D Baleanu +3 more
doaj +1 more source
M-brane Models from Non-Abelian Gerbes
We make the observation that M-brane models defined in terms of 3-algebras can be interpreted as higher gauge theories involving Lie 2-groups. Such gauge theories arise in particular in the description of non-abelian gerbes. This observation allows us to
Palmer, Sam, Saemann, Christian
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

