Results 41 to 50 of about 424,766 (266)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Image Matching by Using Fuzzy Transforms

Advances in Fuzzy Systems, 2013
We apply the concept of Fuzzy Transform (for short, F-transform) for improving the results of the image matching based on the Greatest Eigen Fuzzy Set (for short, GEFS) with respect to max-min composition and the Smallest Eigen Fuzzy Set (for short, SEFS)
Ferdinando Di Martino, Salvatore Sessa
doaj   +1 more source

Why Triangular Membership Functions Are Successfully Used in F-Transform Applications: A Global Explanation to Supplement the Existing Local Ones

Axioms, 2019
The main ideas of F-transform came from representing expert rules. It would be therefore reasonable to expect that the more accurately the membership functions describe human reasoning, the more successful will be the corresponding F-transform formulas ...
Olga Kosheleva, Vladik Kreinovich, Thach Ngoc Nguyen   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Generalized integral Laplace transform and its application to solving some integral equations

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014
We present integral transforms $\widetilde {\mathcal L}\left\{f(t);x\right\}$ and $\widetilde {\mathcal L}_{\gamma_1,\gamma_2,\gamma} \left\{f(t);x\right\}$, generalizing the classical Laplace transform.
Svetlana M Zaikina
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Adaptive Membership Functions and F-Transform

IEEE Transactions on Fuzzy Systems
The definition of the fuzzy-transform (F-transform) has been limited mainly to 1-D signals and 2-D data due to the difficulty of defining membership functions, their centres, and support on a domain with arbitrary dimensionality and topology. We propose a novel method for the adaptive selection of the optimal centres and supports of a class of radial ...
Cammarasana S., Patane Giuseppe
openaire   +2 more sources