Results 61 to 70 of about 424,766 (266)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A method for solving nonlinear Volterra’s population growth model of noninteger order

Advances in Difference Equations, 2017
Many numerical methods have been developed for nonlinear fractional integro-differential Volterra’s population model (FVPG). In these methods, to approximate a function on a particular interval, only a restricted number of points have been employed.
D Baleanu, B Agheli, M Adabitabar Firozja, M Mohamed Al Qurashi   +3 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Combined Reduced-Rank Transform

Symmetry, Integrability and Geometry: Methods and Applications, 2006
We propose and justify a new approach to constructing optimal nonlinear transforms of random vectors. We show that the proposed transform improves such characteristics of {rank-reduced} transforms as compression ratio, accuracy of decompression and ...
Anatoli Torokhti, Phil Howlett
doaj  

The second continuous Jacobi transform

International Journal of Mathematics and Mathematical Sciences, 1985
This paper continues the work started in [1]; a second continuous Jacobi transform is defined for suitable functions f(x). Properties of the transform are studied.
E. Y. Deeba, E. L. Koh
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Generating Suitable Basic Functions Used in Image Reconstruction by F-Transform

Advances in Fuzzy Systems, 2013
Image reconstruction technique based on F-transform uses clearly defined basic functions. These functions have strong impact on the quality of reconstruction. We can use some predefined shape and radius, but also we can create a new one from the scratch.
Pavel Vlašánek
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

On a new Laplace transform formula for shift properties on time scale [PDF]

Mathematica Moravica
We give a new formula of the Laplace transform expressed using the delta derivative for the generalized time scales. This formula F (z) T =LT{f(t)}(z)= ∫∞ 0 ze⊖(z-1)(σ(t),0)f(t)∆t combines the theory of classical Laplace and Z transforms. By choosing the
Mirković Tatjana, Ćirović Nataša
doaj   +1 more source