Results 51 to 60 of about 401,434 (267)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Isometry property and inversion of a spherical mean Radon transform with centers on a hyperplane

AIP Advances
The spherical mean Radon transform maps a suitable function f to the integral of f over a sphere. This transform is used in photoacoustic tomography based on the wave equation.
Jeongmin Kim, Sunghwan Moon
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Relational Variants of Lattice-Valued F-Transforms [PDF]

Axioms, 2019
Two categories of lower and upper lattice-valued F-transforms with fuzzy relations as morphisms are introduced, as generalisations of standard categories of F-transforms with maps as morphisms. Although F-transforms are defined using special structures called spaces with fuzzy partitions, it is shown that these categories are identical to the ...
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Analyticity of replica correlators and modular ETH

Journal of High Energy Physics, 2023
We study the two point correlation function of a local operator on an n-sheeted replica manifold corresponding to the half-space in the vacuum state of a conformal field theory. In analogy with the inverse Laplace transform, we define the Renyi transform
Milind Shyani
doaj   +1 more source

Adaptive Membership Functions and F-Transform

IEEE Transactions on Fuzzy Systems
The definition of the fuzzy-transform (F-transform) has been limited mainly to 1-D signals and 2-D data due to the difficulty of defining membership functions, their centres, and support on a domain with arbitrary dimensionality and topology. We propose a novel method for the adaptive selection of the optimal centres and supports of a class of radial ...
Cammarasana S., Patane Giuseppe
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Wavefield separation using the f–ξ domain for vertical seismic profiling data [PDF]

MATEC Web of Conferences
Wavefield separation is an essential and critical step in data processing of vertical seismic profiles (VSPs). The τ–p transform is one of the effective approaches for separating the VSP wavefield.
Liu Baotong, Liu Qiyuan, Jiang Yingshuang, Liu Donglin, Kang Xuefu   +4 more
doaj   +1 more source