Results 91 to 100 of about 131,324 (287)

Comparative Safety Profiles of Ocrelizumab and Rituximab in Multiple Sclerosis Treatment Using Real‐World Evidence

Annals of Neurology, EarlyView.
Objective The objective of this study was to compare the long‐term safety profiles of ocrelizumab and rituximab in persons with multiple sclerosis (MS). Methods Using retrospective data from the University of California (UC) Health System, we simulated a target clinical trial. The primary cohort from UC San Francisco (UCSF) and a validation cohort from
Gabriel Cerono, Bruce A.C. Cree, Stephen L. Hauser, Sergio E. Baranzini   +3 more
wiley   +1 more source

Non-invasive individual methane measurement in dairy cows

Animal, 2017
Attempts to lower the environmental footprint of milk production needs a sound understanding of the genetic and nutritional basis of methane (CH4) emissions from the dairy production systems. This in turn requires accurate and reliable techniques for the
E. Negussie, J. Lehtinen, P. Mäntysaari, A.R. Bayat, A.-E. Liinamo, E.A. Mäntysaari, M.H. Lidauer   +6 more
doaj   +1 more source

Threshold $J/\psi-$ production in nucleon-nucleon collisions [PDF]

, 2002
We analyze $J/\psi-$ production in nucleon-nucleon collisions near threshold in the framework of a general model independent formalism, which can be applied to any reaction $N+N\to N+N+V^0$, where $V^0=\omega$, $\phi$, or $J/\psi$.
, Bergdolt A M, Bodini L, Caso C, Egle Tomasi-Gustafsson, Golubeva Ye S, Groom D E, Haglin K L, Kodaira J, Matinyan S G, Michail P Rekalo, Redlich K, Sibirtsev A, Sibirtsev A, Titov A I, Wang X N, Wen-Tai Chiang   +16 more
core   +3 more sources

Migration and invasion in B16-F10 mouse melanoma cells are regulated by Nrf2 inhibition during treatment with ionizing radiation.

Oncology Letters, 2018
Nuclear factor erythroid 2-related factor 2 (Nrf2) serves a critical role in carcinogenesis. The present study examined the effect of Nrf2 on the proliferation and invasion of melanoma cells that were treated with ionizing radiation.
Ya-Li Gao, Zishen Zhao, Xiaoyin Meng, Hong-gui Chen, Guojun Fu   +4 more
semanticscholar   +1 more source

Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case–Control Study and Call for a Consensus

Annals of Neurology, EarlyView.
Objective Sleep‐predominant network hyperexcitability is increasingly recognized as a potential disease‐accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk‐factors remain debated, largely due to cohort‐specific and methodological differences across studies.
Anna B. Szabo, Jonathan Curot, Fleur Gérard, Florence Rulquin, Rachel Debs, Claire Georges, Marie Denuelle, Amel Bouloufa, Béatrice Lemesle, Patrice Péran, Claire Thalamas, Emmanuel J. Barbeau, Jérémie Pariente, Lionel Dahan, Luc Valton   +14 more
wiley   +1 more source

Outflows in rho Ophiuchi as Seen with the Spitzer Infrared Array Camera

, 2009
Using the IRAC images from the Spitzer c2d program, we have made a survey of mid-infrared outflows in the rho Ophiuchi molecular cloud. Extended objects that have prominent emission in IRAC channel 2 (4.5 micron) compared to IRAC channel 1 (3.6 micron ...
Allen, Andrews, André, Arce, Bally, Barsony, Bary, Bitner, Bontemps, Bouvier, Bussmann, Cyganowski, de Zeeuw, Dent, Dunham, Eislöffel, Evans, Gómez, Gómez, Hirano, Hongchi Wang, Imanishi, Johnstone, Johnstone, Jørgensen, Lis, Merín, Miaomiao Zhang, Motte, Noriega-Crespo, Padgett, Phelps, Reach, Ridge, Rosenthal, Shang, Smith, Smith, Stark, Visser, Wilking, Wilking, Wilking, Wilson, Wu, Young   +45 more
core   +1 more source

A flexible and highly sensitive pressure sensor based on a PDMS foam coated with graphene nanoplatelets [PDF]

, 2016
The demand for high performance multifunctional wearable devices is more and more pushing towards the development of novel low-cost, soft and flexible sensors with high sensitivity.
Fortunato, Marco, Rinaldi, Andrea, Sarto, Maria Sabrina, Tamburrano, Alessio   +3 more
core   +2 more sources

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

HIF-1α acts as a molecular target for simvastatin cytotoxicity in B16.F10 melanoma cells cultured under chemically induced hypoxia.

Oncology Letters, 2017
Our previous studies reported that one of the main mechanisms of the antitumor activity of simvastatin (SIM) in B16.F10 murine melanoma cells was associated with strong suppression of the constitutive cell production of the α subunit of the heterodimeric
E. Licărete, Alina Sesarman, V. Rauca, Lavinia Luput, Laura Pătraș, Manuela Banciu   +5 more
semanticscholar   +1 more source

Comparative Analysis of Septin Modifiers, Forchlorfenuron and UR214‐9, on Mitochondrial Fragmentation and Lytic Cell Death

Cytoskeleton, EarlyView.
ABSTRACT Septins are conserved GTP‐binding proteins that play key roles in cell division, mitochondrial dynamics and immune responses. Despite their importance to human health, pharmacological compounds to modify septins remain limited. Forchlorfenuron (FCF) was the first small molecule identified to modify septins, disrupting their organisation and ...
Dominik Brokatzky, Rajdeep Das, Hannah Painter, Rakesh K. Singh, Serge Mostowy   +4 more
wiley   +1 more source