Results 71 to 80 of about 125,843 (323)

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Non-invasive individual methane measurement in dairy cows

Animal, 2017
Attempts to lower the environmental footprint of milk production needs a sound understanding of the genetic and nutritional basis of methane (CH4) emissions from the dairy production systems. This in turn requires accurate and reliable techniques for the
E. Negussie, J. Lehtinen, P. Mäntysaari, A.R. Bayat, A.-E. Liinamo, E.A. Mäntysaari, M.H. Lidauer   +6 more
doaj   +1 more source

Comparison of the cytotoxic effects of different fractions of Artemisia ciniformis and Artemisia biennis on B16/F10, PC3 and MCF7 Cells

Research in Pharmaceutical Sciences, 2020
Background and purpose: Artemisia is one of the well-known herbal medicinal plants for antimicrobial, insecticidal, antioxidant, and antimalarial activities. The antiproliferative effects of dichloromethane extracts of Artemisia biennis (A.
Elham Ramazani, Zahra Tayarani-Najaran, Yalda Shokoohinia, Mahdi Mojarrab   +3 more
doaj   +1 more source

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

Advanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang, Qiqi Qi, Dezhong Li, Jingshi Tang, Weifeng Wang, Zushun Xu, Qi Xu, Fangfang Du, Qianyuan He   +8 more
wiley   +1 more source

Force and torque acting on particles in a transitionally rough open channel flow

, 2011
Direct numerical simulation of open channel flow over a geometrically rough wall has been performed at a bulk Reynolds number of approximately 2900. The wall consisted of a layer of spheres in a square arrangement. Two cases have been considered.
Bayazit, Clemens Chan-Braun, Detert, Manuel García-Villalba, Markus Uhlmann, Nezu, Nikuradse, Pokrajac, Schlichting, Shields, Townsend, Uhlmann, Uhlmann, van Rijn   +13 more
core   +1 more source

Supplementary Figure 1A from Lysophosphatidylcholine Pretreatment Reduces VLA-4 and P-Selectin–Mediated B16.F10 Melanoma Cell Adhesion <i>In vitro</i> and Inhibits Metastasis-Like Lung Invasion <i>In vivo</i> [PDF]

, 2023
Peter Jantscheff, Martin Schlesinger, Juliane Fritzsche, Lenka A. Taylor, Ralph Graeser, Gregor Kirfel, Dieter O. Fürst, Ulrich Massing, Gerd Bendas   +8 more
openalex   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

In Quantum Computing Speedup Illusory?: The False Coin of "Counting Function Evaluations"

, 2020
By using a new way to encode Boolean functions in a reversible gate, an algorithm is developed in quantum computing over Z_2, symbolized QC/2, (as opposed to QC over C) that needs only one function evaluation to solve the Grover Database Search Problem ...
Ellerman, David
core  

Non‐Uniform Space‐Time‐Coding Modulation for Low‐Complexity Diagnostics of Reconfigurable Intelligent Surfaces

Advanced Electronic Materials, EarlyView.
A diagnostic method for reconfigurable intelligent surfaces (RIS) based on non‐uniform space‐time‐coding modulation is presented. Fault localization is achieved via amplitude‐only spectral measurements, eliminating the need for complex signal processing. A one‐to‐one mapping between harmonic components and RIS elements enables accurate detection.
Xiao Qing Chen, Lei Zhang, Yi Ning Zheng, Bing Bing Zhu, Marco Rossi, Giuseppe Castaldi, Shuo Liu, Vincenzo Galdi, Tie Jun Cui   +8 more
wiley   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source