Results 61 to 70 of about 123,710 (270)

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

open access: yesAdvanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang   +7 more
wiley   +1 more source

Emerging Varieties of Capitalism in Transition Countries: Literature Review

open access: yesInternational Journal of Management and Economics, 2015
The systemic transformation of post-socialist countries from central planning to a market economy was a very complex and unprecedented undertaking. In this study we critically examine three influential classifications proposed by Coates [2000, 2006 ...
Leszczyński Dariusz
doaj   +1 more source

Low energy behaviour of standard model extensions [PDF]

open access: yes, 2016
The integration of heavy scalar fields is discussed in a class of BSM models, containing more that one representation for scalars and with mixing. The interplay between integrating out heavy scalars and the Standard Model decoupling limit is examined. In
Boggia, Michele   +2 more
core   +2 more sources

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun   +15 more
wiley   +1 more source

Non-invasive individual methane measurement in dairy cows

open access: yesAnimal, 2017
Attempts to lower the environmental footprint of milk production needs a sound understanding of the genetic and nutritional basis of methane (CH4) emissions from the dairy production systems. This in turn requires accurate and reliable techniques for the
E. Negussie   +6 more
doaj   +1 more source

Comparison of the cytotoxic effects of different fractions of Artemisia ciniformis and Artemisia biennis on B16/F10, PC3 and MCF7 Cells

open access: yesResearch in Pharmaceutical Sciences, 2020
Background and purpose: Artemisia is one of the well-known herbal medicinal plants for antimicrobial, insecticidal, antioxidant, and antimalarial activities. The antiproliferative effects of dichloromethane extracts of Artemisia biennis (A.
Elham Ramazani   +3 more
doaj   +1 more source

2D Quantum Hydrogen Atom in Circularly Polarized Microwaves

open access: yes, 1995
The ionization of hydrogen Rydberg atoms by circularly polarized microwaves is studied quantum mechanically in a model two dimensional atom. We apply a combination of a transformation to the coordinate frame rotating with the field, with complex rotation
Delande, Dominique   +2 more
core   +1 more source

On Almost Paracontact Almost Paracomplex Riemannian Manifolds [PDF]

open access: yes, 2018
Almost paracontact manifolds of an odd dimension having an almost paracomplex structure on the paracontact distribution are studied. The components of the fundamental (0,3)-tensor, derived by the covariant derivative of the structure endomorphism and the
Manev, Mancho, Tavkova, Veselina
core   +2 more sources

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li   +8 more
wiley   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

open access: yesAdvanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong   +21 more
wiley   +1 more source

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