Engaging in cross‐disciplinary collaboration to enhance knowledge of historical design
Abstract The purpose of this research was to understand students' experiences engaging in cross‐disciplinary object‐based learning activities. A cross‐disciplinary approach was employed to help students draw connections between clothing and residential housing styles to fill gaps in research within cross‐disciplinary contexts involving two family and ...
Dina Smith‐Glaviana +2 more
wiley +1 more source
Determining the Critical Period of Continuous Waterlogging in Maize: An Analysis of Physiological, Biochemical, and Transcriptomic Traits. [PDF]
Chen D +7 more
europepmc +1 more source
Reduced Dietary Protein Induces Changes in the Dental Proteome
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs +2 more
wiley +1 more source
Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu +16 more
wiley +2 more sources
Colorectal Cancer: Differential Gene Expression and In Vitro Response to 5-Fluorouracil, Novel Fluoropyrimidine F10, and Potential Synergy with Lupeol. [PDF]
Thaker SD +6 more
europepmc +1 more source
ABSTRACT Introduction Global functioning is a common clinician‐rated measure of treatment changes in inpatient psychiatric care, but its broad scope may limit its sensitivity to specific mental health changes. This study aimed to research interplay and improvements of global functioning and several mental health parameters.
Alexander Finner +12 more
wiley +1 more source
Targeting PDPN enhances antitumor T-cell activity by disrupting β-catenin-mediated PD-L1 expression in melanoma. [PDF]
Feng C +5 more
europepmc +1 more source
This article analyses future projections of ocean properties for a region of the south‐west Pacific Ocean encompassing the New Zealand Exclusive Economic Zone under different climate change emission scenarios. Projections are updated and expanded from previous assessments using a “best” ensemble comprising both CMIP5 and CMIP6 earth system models.
Graham J. Rickard +2 more
wiley +1 more source
Abstract Aim To examine the socioeconomic differences in the effectiveness of alcohol use disorders (AUD) pharmacotherapy and risk of AUD hospitalisation. Design A prospective register‐based cohort study. Setting Sweden. Participants Individuals who were registered as living in Sweden in 2005 (16–64 years) with a first‐time AUD diagnosis and complete ...
Devy L. Elling +6 more
wiley +1 more source
Anti-VEGF immunotherapy with HEBERSaVax suppresses melanoma growth and metastasis via angiogenesis blockade and enhanced T-cell infiltration. [PDF]
Morera-Díaz Y +13 more
europepmc +1 more source

