Results 31 to 40 of about 44,344 (261)

Five new F10 variants in hereditary factor x deficiency detected by high-throughput sequencing

, 2023
International audienceIntroduction - Factor X deficiency is a rare inherited bleeding disorder. To date, 181 variants are reported in the recently updated F10-gene variant database. Aim - This study aimed to describe new F10 variants.
Wahl, Clementine, Guillet, Benoit, Pastoret, Cédric, Castet, Sabine, Nédelec-Gac, Fabienne, Pontis, Adeline, Fest, Thierry, Bayart, Sophie   +7 more
core   +1 more source

In vitro anti-melanoma effect of polyphenolic compounds

Asian Pacific Journal of Tropical Biomedicine, 2022
Objective: To evaluate the effects of phenolic acids (caffeic, ferulic, and coumaric acids) and flavones (luteolin and apigenin) on the proliferation and melanogenesis in murine melanoma B16-F10 cells. Methods: Cell proliferation was determined after 24
Fairouz Sioud, Mouna Maatouk, Imen Mokdad Bzeouich, Leila Chekir Ghedira, Soumaya Kilani-Jaziri   +4 more
doaj   +1 more source

Exercise does not change tumour cell proliferation in B16-F10 or EO771 tumours.

, 2020
(a) Representative immunohistochemical staining for pHH3, a mitotic marker, in tumour sections from exercising vs non-exercising mice with B16-F10 melanoma or EO771 breast cancer.
Abel D. Ang (8595348), Gabi U. Dachs (8595360), Linda A. Buss (8595345), Bridget A. Robinson (8595354), Margaret J. Currie (8595357), Barry Hock (8595351)   +5 more
core   +1 more source

Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition

Neoplasia: An International Journal for Oncology Research, 2018
We are developing the fluoropyrimidine polymer F10 to overcome limitations of 5-fluorouracil (5-FU) that result from inefficient metabolism to 5-fluoro-2′-deoxyuridine-5′-mono- and tri-phosphate, the deoxyribonucleotide metabolites that are responsible ...
Chinnadurai Mani, Sachin Pai, Cinta Maria Papke, Komaraiah Palle, William H. Gmeiner   +4 more
doaj   +1 more source

B16‐F10 melanoma cells

, 2003
Sequentially treating human melanoma cell lines by priming with interferon-gamma before adding interferon-beta was previously found to be the most efficient protocol for producing concurrently increased expression of the three surface antigens B7-1 ...
Stephen J Ralph, Hatzinisiriou, I, Irene Hatzinisiriou, Dezfouli, S, Shala Dezfouli, Ralph, SJ   +5 more
core   +1 more source

EO771 tumours are more proliferative, more vascular and more hypoxic than B16-F10 tumours.

, 2020
Exercising and non-exercising mice were pooled for this analysis as no difference was seen with exercise. (a) Quantification of the percentage of pHH3+ cells in B16-F10 vs EO771 tumours.
Abel D. Ang (8595348), Gabi U. Dachs (8595360), Linda A. Buss (8595345), Bridget A. Robinson (8595354), Margaret J. Currie (8595357), Barry Hock (8595351)   +5 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Plots of “sandwich SPR” showing the binding kinetics of B-F10 or A-23 binding to HSP as a secondary antibody in a sandwich assay in which HSP was first captured by A-23 or B-F10.

, 2013
Four different sandwich variations are shown: A-23-HSP-A-23 or -B-F10 (top panel) and B-F10-HSP-A-23 or -B-F10 (lower panel).
Natalie J. Thompson (416798), Saurabh K. Srivastava (341055), Vincent J. B. Ruigrok (416797), Albert J. R. Heck (9680), Maarten A. Jongsma (69686), Jules Beekwilder (45525), Cees van Rijn (416799), Anke K. Trilling (341050)   +7 more
core   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Sectoral evidence on Indonesian economic performance after the pandemic

Asia and the Global Economy, 2023
The Indonesian economy has a long history of steady growth punctuated by times of turmoil and crisis. Recently Indonesia has faced the COVID-19 pandemic, inflation, contractionary U.S. monetary policy, and fluctuating commodity prices. To examine how the
Willem Thorbecke
doaj   +1 more source