Results 61 to 70 of about 131,324 (287)

Fast rate of convergence in high dimensional linear discriminant analysis

, 2010
This paper gives a theoretical analysis of high dimensional linear discrimination of Gaussian data. We study the excess risk of linear discriminant rules.
Girard, Robin
core   +3 more sources

Ginkgo biloba Exocarp Extract Inhibits the Metastasis of B16-F10 Melanoma Involving PI3K/Akt/NF-κB/MMP-9 Signaling Pathway

Evidence-Based Complementary and Alternative Medicine, 2018
In recent years, interest in natural plant extracts for cancer treatment is growing in the drug development field. Ginkgo biloba exocarp extract (GBEE) is known for possessing inhibitory effects on various mouse and human cancer cells.
Chenjie Cao, Ya Su, Yanqi Gao, Chengrong Luo, Lu Yin, Yingjie Zhao, Hua-sheng Chen, A. Xu   +7 more
semanticscholar   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Exploring protandry and pupal size selection for Aedes albopictus sex separation [PDF]

, 2018
Background: We explored the possibility to improve male/female separation (sexing) in Aedes albopictus by selection of two strains, one toward increasing sex dimorphism and another toward increasing protandry.
Balestrino, Fabrizio, Bellini, Romeo, Carrieri, Marco, Puggioli, Arianna, Urbanelli, Sandra   +4 more
core   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Restrictions applied by WTO countries in international trade in the context of the COVID-19 pandemic

International Journal of Management and Economics
The present article discusses changes in tariff and non-tariff restrictions applied in World Trade Organization (WTO) countries during the COVID-19 pandemic.
Fronczek Małgorzata
doaj   +1 more source

Combination therapy of simvastatin and 5, 6-dimethylxanthenone-4-acetic acid synergistically suppresses the aggressiveness of B16.F10 melanoma cells

PLoS ONE, 2018
The major drawback of current anti-angiogenic therapies is drug resistance, mainly caused by overexpression of the transcription factor, hypoxia-inducible factor 1α (HIF-1α) as a result of treatment-induced hypoxia, which stimulates cancer cells to ...
V. Rauca, E. Licărete, Lavinia Luput, Alina Sesarman, Laura Pătraș, P. Bulzu, E. Rakosy-Tican, Manuela Banciu   +7 more
semanticscholar   +1 more source

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Force and torque acting on particles in a transitionally rough open channel flow

, 2011
Direct numerical simulation of open channel flow over a geometrically rough wall has been performed at a bulk Reynolds number of approximately 2900. The wall consisted of a layer of spheres in a square arrangement. Two cases have been considered.
Bayazit, Clemens Chan-Braun, Detert, Manuel García-Villalba, Markus Uhlmann, Nezu, Nikuradse, Pokrajac, Schlichting, Shields, Townsend, Uhlmann, Uhlmann, van Rijn   +13 more
core   +1 more source

Two-loop neutrino masses with large R-parity violating interactions in supersymmetry [PDF]

, 2008
We attempt to reconcile large trilinear R-parity violating interactions in a supersymmetric (SUSY) theory with the observed pattern of neutrino masses and mixing.
A. Bandyopadhyay, Anirban Kundu, B. Mukhopadhyaya, Biswarup Mukhopadhyaya, G. Bhattacharyya, H.K. Dreiner, J. Welzel, J.N. Bahcall, M.V. Garzelli, Paramita Dey, R. Barbier ., Soumitra Nandi, V. Lubicz   +12 more
core   +2 more sources