Results 161 to 170 of about 16,053 (201)

F35

2018
  +8 more sources

Efficient gene transfer into normal human B lymphocytes with the chimeric adenoviral vector AD5/F35

Journal of Immunological Methods, 2005
The failure to efficiently introduce genes into normal cells such as human B lymphocytes limits the characterization of their function on cellular growth, differentiation and survival. Recent studies have shown that a new adenoviral vector Ad5/F35 can efficiently transduce human haematopoietic CD34+ progenitor cells. In this study, we compared the gene
Sonia Néron
exaly   +3 more sources

Intracellular trafficking and fate of chimeric adenovirus 5/F35 in human B lymphocytes

Journal of Gene Medicine, 2011
AbstractBackgroundInvestigation of the molecular processes that control the development and function of lymphocytes is essential for our understanding of humoral immunity, as well as lymphocyte‐associated pathogenesis. Adenovirus‐mediated gene transfer provides a powerful tool for investigating these processes.
Mélanie, Samson, Daniel, Jung
exaly   +3 more sources

CCWi2017: F35 'FRACTALITY IN WATER DISTRIBUTION NETWORKS'

2017
Fractals have been identified as a common feature of many natural and artificial systems that exhibit similar patterning at different scales. Understanding fractals is a critical aspect of decoding complex systems, as the pattern of such large systems can be revealed by identifying only a small part of the system.
Kegong Diao, Butler, David, Ulanicki, Bogumil   +2 more
openaire   +1 more source

Preclinical Assessment ofFHITGene Replacement Therapy in Human Leukemia Using a Chimeric Adenovirus, Ad5/F35

Clinical Cancer Research, 2006
AbstractPurpose: Expression of the FHIT protein is lost or reduced in most solid tumors and a significant fraction of hematopoietic malignancies. Adenovirus 5 (Ad5) virus or adeno-associated viral vectors have been used to study the tumor suppressor function of FHIT in solid tumors, but these tools have not been effective in leukemias.
PICHIORRI F, TRAPASSO F, PALUMBO T, AQEILAN RI, DRUSCO A, BLASER BW, ILIOPOULOS D, CALIGIURI MA, HUEBNER K, CROCE, Carlo Maria   +9 more
openaire   +2 more sources

Comparison of promoter activities for efficient expression into human B cells and haematopoietic progenitors with adenovirus Ad5/F35

Journal of Immunological Methods, 2007
Adenoviral gene transfer into human B lymphocytes and haematopoietic progenitors would allow the characterization of their function on cellular growth, differentiation and survival. Efficient gene expression is however strongly dependent on the promoter used.
Audrey Forest, Nicolas Pineault
exaly   +3 more sources

F35. Prevalence of nerve conduction abnormalities in type 1 diabetes mellitus

Clinical Neurophysiology, 2018
Introduction Diabetic peripheral neuropathy (DPN) is the commonest microvascular complication in diabetic patients. Unlike type-2 DM, children with type-1 DM rarely develop the classical features of neuropathy. Nerve conduction study (NCS) is an objective, non-invasive electrophysiological test for diagnosing DPN The aim of this study is to detect and
openaire   +1 more source

F35 Ground Investigation Monitoring, RAF Lakenheath, Suffolk, Archaeological Monitoring Report

2018
Several geotechnical ground investigation works were monitored, mainly on the southern side of RAF Lakenheath, across the parishes of Eriswell and Lakenheath, Suffolk. The works recorded no features or finds, but generally the soil profiles appeared well preserved, with any significant levels of modern truncation being isolated.
openaire   +1 more source

F35 The contribution of motor speed to performance on cognitive processing tasks in huntington’s disease

Clinical studies, 2018
Background Cognitive processing speed has been found to be slower in those with manifest and premanifest Huntington’s disease (Maroof, Gross & Brandt, 2011) compared to controls. However, the most commonly employed measures of cognitive processing speed, such as the Stroop Test, Symbol Digit Modalities Test and Trail Making, all rely on motor ...
Laura Sherlock, Sarah Mason, Roger Barker   +2 more
openaire   +1 more source

E1B 55‐kDa deleted, Ad5/F35 fiber chimeric adenovirus, a potential oncolytic agent for B‐lymphocytic malignancies

The Journal of Gene Medicine, 2009
AbstractBackgroundConditionally replicative adenovirus (CRAd) provides a promising strategy for solid tumor therapy. However, relatively few studies have been addressed on hematopoietic malignancies. We previously found that ZD55, a serotype 5 (Ad5)‐based, E1B 55‐kDa deleted CRAd, inhibited leukemic cell growth and induced apoptosis.
Guohua, Wang, Gongchu, Li, Hui, Liu, Chunmei, Yang, Xiudi, Yang, Jie, Jin, Xinyuan, Liu, Qijun, Qian, Wenbin, Qian   +8 more
openaire   +2 more sources