Results 121 to 130 of about 17,763 (210)

Clinical and molecular features of PRCD‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin, Karolina Kaminska, Marco Cattaneo, Enrico Ambrosini, Carmen Ayuso, Almudena Ávila‐Fernández, Béatrice Bocquet, Luisa Coutinho‐Santos, Benedetto Falsini, Lidia Fernandez‐Caballero Palomeque, Bohdan Kousal, Petra Liskova, Inmaculada Martín‐Mérida, María Juliana Ballesta‐Martínez, Daan Panneman, Susanne Roosing, Isabelle Meunier, José M. Millán, Monika Pankievič, Irene Perea‐Romero, Virginie Peter, Giorgio Placidi, Cristina Santos, Francesca Simonelli, Ana Berta Sousa, Francesco Testa, Marie Vajter, Marianna Weener, Mathieu Quinodoz, Carlo Rivolta, Giacomo Calzetti   +30 more
wiley   +1 more source

Extending reliability to intensive longitudinal data with the Kalman filter

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Reliability is central to how researchers approach measurement in standard, group‐based analyses of single‐time‐point data, yet this critical aspect is often overlooked in the analysis of repeated observations. Since its inception, reliability has been a between‐person concept, but we redevelop this notion for within‐person designs by ...
Michael D. Hunter
wiley   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

Serendipitous Explanations: Interaction‐Triggered Comprehension Aids in Visualization

Computer Graphics Forum, EarlyView.
Abstract Evidence continues to accrue around the difficulties people have understanding new and complex visualizations, which in turn provides continued incentive to explore additional methods of supporting visualization viewers. Through leveraging viewers' spontaneous visualization sensemaking activities, we introduce a Serendipitous Explanation ...
M. Rezaie, M. Tory, S. Carpendale
wiley   +1 more source

Stoichiometric and Catalytic C-C and C-H Bond Formation with B(C6 F5 )3 via Cationic Intermediates.

Angewandte Chemie, 2017
Yashar Soltani, Lewis C Wilkins, Rebecca L. Melen   +2 more
semanticscholar   +1 more source

Rendering Synthetic Defects for Learning‐Based Industrial Inspection

Computer Graphics Forum, EarlyView.
Abstract Computer vision increasingly uses synthetic data from physically based rendering to supplement limited real‐world datasets. In industrial inspection, defect data is scarce and the rendering pipeline is explicitly controlled, and synthetic defect generation therefore becomes a dataset design problem.
Runzhou Mao, Hiroyuki Sakai, Christian Freude, Christoph Garth, Petra Gospodnetić, Juraj Fulir   +5 more
wiley   +1 more source

Impact of an Educational Intervention on Dental Students' Practical Motivation in Early Oral Cancer Detection: Assessment With the “Perceived Locus of Causality–University Version” Questionnaire

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Early detection of oral cancer significantly improves prognosis, but diagnostic delays persist due to professional and educational factors. This study aimed to evaluate the impact of an educational intervention on dental students' motivation toward oral cancer detection, using the Perceived Locus of Causality–University Version ...
Esther Delgado‐Somolinos, Jesus Rodriguez‐Molinero, Blanca del Carmen Miguelañez‐Medrán, Rosario Ramírez‐Puerta, Inmaculada Corral‐Liria, Marta Elena Losa‐Iglesias, Manuel Norberto Sánchez‐de Miguel, Antonio Francisco López‐Sánchez   +7 more
wiley   +1 more source

Risk management strategies in higher education

European Management Review, EarlyView.
Abstract Higher education centres are facing escalating risks, such as increasing competition from a growing number of higher education organisations, as well as greater exposure to more complex regulatory frameworks and external evaluations. Consequently, university risk management has assumed increasing significance.
Washington Guevara‐Piedra, Carmen González‐Zapatero, Javier González‐Benito   +2 more
wiley   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

The FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner, Douglas M. M. Soares, Bianca B. Nóbrega, Etelvino J. H. Bechara, Zinaida M. Kaskova, Alexander S. Mishin, Karen S. Sarkisyan, Ilia V. Yampolsky, Cassius V. Stevani   +8 more
wiley   +1 more source

Ploidy‐dependent modulation of DNA replication kinetics in Xenopus

The FEBS Journal, EarlyView.
Using an interspecies replication system with Xenopus frog species of different ploidy levels, we investigated how DNA replication adapts to polyploidization. While replication was slower in tetraploid than in diploid nuclei, dodecaploid nuclei unexpectedly replicated faster than tetraploid nuclei. Our findings show that increasing genome size does not
Hemalatha Narassimprakash, Olivier Haccard, Zhen Li, Nicolas Pollet, Kathrin Marheineke   +4 more
wiley   +1 more source