Results 191 to 200 of about 1,231,086 (256)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Doped Biopolymer Composites for Engineered Water Purification: Mechanistic Insights into Multi-Ion Adsorption. [PDF]

Ind Eng Chem Res
Maroulas KN, Tolkou AK, Ladomenou K, Drivas C, Isaacs MA, Ntougias S, Katsoyiannis IA, Kyzas GZ.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Metacognitive strategies to optimise cognitive and metacognitive abilities among individuals with cognitive communication disorders and neurotypical adults: a scoping review. [PDF]

BMJ Open
Rooha A, Sinchana S, Jacob NL, Bajaj G, Chaudhary C, George VM, Bhat JS.   +6 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The Metabolic Diversity of Different Salsola Species Valorized Through Untargeted Metabolomics and In Vitro Bioassays: The Importance of Phenolic Constituents. [PDF]

Plants (Basel)
Salehi H, Gregorio MA, Zengin G, Yagi S, Ak G, Saka E, Elbasan F, Yildiztugay E, Zhang L, Dall'Acqua S, Lucini L.   +10 more
europepmc   +1 more source

Integrin activation by two independently regulated calcium-mediated pathways is required for neutrophil recruitment. [PDF]

Cell Commun Signal
Oguama M, Lindental P, Clemens RA, Lowell CA, Soehnlein O, Roth J, Bakchoul T, Cappenberg A, Zarbock A.   +8 more
europepmc   +1 more source

Symptom clusters in oesophageal cancer patients during varying phases of postoperative chemotherapy: a scoping review. [PDF]

BMJ Open
Zhi Q, Liao Y, Ke H, Wang H, Zhan Y, Wang W, Li W, Liu Y, Yu J.   +8 more
europepmc   +1 more source