FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PCA BASED Image Fusion of Face and Iris Biometric Features
, 2020 Sanjay Nair, P. Aruna, M. Vadivukarassi
openalex +1 more source
Emotion-Mind Dynamic (EMD): Face-to-face and online blended-learning life coaching for a social prescribing intervention to support mental health and wellbeing: Protocol for a Social Return on Investment evaluation [PDF]
, 2022 Mary Lynch +5 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Challenges of Higher Education Students Face in Using Artificial Intelligence (AI) against Their Learning Experiences [PDF]
Amy Liew Xiu Jie +1 more
openalex +1 more source
Generative Adversarial Networks for anonymous Acneic face dataset generation [PDF]
, 2022 Hazem Zein +3 more
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Crítica, afetividade e criação de sentidos nos Estudos Organizacionais
Revista Espaço Acadêmico, 2013 O texto, que originalmente foi um exposição realizada no I Colóquio Internacional de Estudos Organizacionais, explora a atualidade do pensamento de Maurício Tragtenberg em suas proposições sobre a delinquência acadêmica.
Ana Paula Paes de Paula
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