Results 71 to 80 of about 448,084 (278)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Forming Facial Expressions Influences Assessment of Others' Dominance but Not Trustworthiness

Frontiers in Psychology, 2017
Forming specific facial expressions influences emotions and perception. Bearing this in mind, studies should be reconsidered in which observers expressing neutral emotions inferred personal traits from the facial expressions of others.
Yoshiyuki Ueda, Kie Nagoya, Sakiko Yoshikawa, Michio Nomura   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Video Assessment to Detect Amyotrophic Lateral Sclerosis

Digital Biomarkers
Introduction: Weakened facial movements are early-stage symptoms of amyotrophic lateral sclerosis (ALS). ALS is generally detected based on changes in facial expressions, but large differences between individuals can lead to subjectivity in the diagnosis.
Guilherme Camargo Oliveira, Quoc Cuong Ngo, Leandro Aparecido Passos, Leonardo Silva Oliveira, Stella Stylianou, João Paulo Papa, Dinesh Kumar   +6 more
doaj   +1 more source

Efficient recognition of facial expressions does not require motor simulation

eLife, 2020
What mechanisms underlie facial expression recognition? A popular hypothesis holds that efficient facial expression recognition cannot be achieved by visual analysis alone but additionally requires a mechanism of motor simulation — an unconscious, covert
Gilles Vannuscorps, Michael Andres, Alfonso Caramazza   +2 more
doaj   +1 more source

A Survey of the Trends in Facial and Expression Recognition Databases and Methods

, 2015
Automated facial identification and facial expression recognition have been topics of active research over the past few decades. Facial and expression recognition find applications in human-computer interfaces, subject tracking, real-time security ...
Emmons, Michelle, Roychowdhury, Sohini
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A Two-Stage Facial Kinematic Control Strategy for Humanoid Robots Based on Keyframe Detection and Keypoint Cubic Spline Interpolation

Mathematics
A plentiful number of facial expressions is the basis of natural human–robot interaction for high-fidelity humanoid robots. The facial expression imitation of humanoid robots involves the transmission of human facial expression data to servos situated ...
Ye Yuan, Jiahao Li, Qi Yu, Jian Liu, Zongdao Li, Qingdu Li, Na Liu   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source