Results 81 to 90 of about 3,888,868 (294)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Two-Stage Facial Kinematic Control Strategy for Humanoid Robots Based on Keyframe Detection and Keypoint Cubic Spline Interpolation

Mathematics
A plentiful number of facial expressions is the basis of natural human–robot interaction for high-fidelity humanoid robots. The facial expression imitation of humanoid robots involves the transmission of human facial expression data to servos situated ...
Ye Yuan, Jiahao Li, Qi Yu, Jian Liu, Zongdao Li, Qingdu Li, Na Liu   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Video Assessment to Detect Amyotrophic Lateral Sclerosis

Digital Biomarkers
Introduction: Weakened facial movements are early-stage symptoms of amyotrophic lateral sclerosis (ALS). ALS is generally detected based on changes in facial expressions, but large differences between individuals can lead to subjectivity in the diagnosis.
Guilherme Camargo Oliveira, Quoc Cuong Ngo, Leandro Aparecido Passos, Leonardo Silva Oliveira, Stella Stylianou, João Paulo Papa, Dinesh Kumar   +6 more
doaj   +1 more source

Efficient recognition of facial expressions does not require motor simulation

eLife, 2020
What mechanisms underlie facial expression recognition? A popular hypothesis holds that efficient facial expression recognition cannot be achieved by visual analysis alone but additionally requires a mechanism of motor simulation — an unconscious, covert
Gilles Vannuscorps, Michael Andres, Alfonso Caramazza   +2 more
doaj   +1 more source

Empirical investigation of the temporal relations between speech and facial expressions of emotion [PDF]

, 2009
Lien vers l'article original : http://link.springer.com/article/10.1007/s12193-010-0050-4Behavior models implemented within Embodied Conversational Agents (ECAs) require nonverbal communication to be tightly coordinated with speech.
BUISINE, Stéphanie, WANG, Yun, Yun Wang, Stéphanie Buisine, GRYNSZPAN, Ouriel, Ouriel Grynszpan   +5 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

What Happens in Face During a Facial Expression? Using Data Mining Techniques to Analyze Facial Expression Motion Vectors [PDF]

Automatic facial expression recognition is a big challenge in human–computer interaction. Analyzing the changes in the face during a facial expression can be used for this purpose. In this paper, these changes are extracted as a number of motion vectors.
Shoeibi, Afshin, Gorriz, Juan M., Nahavandi, Saeid, Roshanzamir, Mahdi, Roshanzamir, Mohamad, Alizadehsani, Roohallah, Jafari, Mahboobeh, Acharya, U. Rajendra, Khosravi, Abbas   +8 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source