Results 141 to 150 of about 124,185 (265)

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Facial pain assessment based on contrastive learning

open access: yes四川大学学报. 自然科学版
Automatic pain assessment has great clinical application prospects and has attracted great attention, because it is feasible to recognize facial pain through facial visual information.Existing methods mostly focus on extracting features of different ...
XU Ri-Sheng   +3 more
doaj  

From Chatbots to Co‐Scientists: The Impact of Knowledge‐Generating AI (AI 4.0) on Healthcare and Research

open access: yesAdvanced Science, EarlyView.
This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley   +1 more source

Internal neurolysis for atypical facial pain: Clinical outcomes and validation of an intraoperative trigeminal pathology scoring system. [PDF]

open access: yesSurg Neurol Int
Onoda K   +14 more
europepmc   +1 more source

Absorption of Broadband Low‐Frequency Sound Beyond the Thermodynamics Limit: An Acoustic Resonator With Magnetic Bearing

open access: yesAdvanced Science, EarlyView.
This work presents a magnetic‐bearing acoustic resonator that overcomes the thermodynamics limit of sound absorption. By introducing tunable negative stiffness, it achieves broadband low‐frequency absorption within a compact cavity, far exceeding the performance achievable by classic mass‐tuned designs.
Ying Hu   +5 more
wiley   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

open access: yesAdvanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou   +10 more
wiley   +1 more source

Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics

open access: yesAdvanced Science, EarlyView.
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley   +1 more source

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