Results 131 to 140 of about 826,590 (334)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The importance of understanding the multiple dimensions of power in stakeholder participation for effective biodiversity conservation

open access: yesPeople and Nature
Biodiversity conservation are increasingly focused on involving stakeholder engagement, making power a key concept in understanding its success and failure.
L. Lécuyer   +12 more
doaj   +1 more source

Quantifying the Benefits of Trade Facilitation in ASEAN [PDF]

open access: yes
This paper assesses the performance and progress of the ASEAN economies in trade facilitation, and the effect of improved trade facilitation on the regionfs manufacturing trade with a focus on port efficiency, customs environment, regulatory environment ...
Tsunehiro Otsuki
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Positive interactions in ecology: filling the fundamental niche

open access: yesIdeas in Ecology and Evolution, 2012
The role of negative interactions in shaping ecological communities and the realized niches of species has been a focus of considerable research for at least decades.
Mariano A. Rodriguez-Cabal   +2 more
doaj  

Customs Valuation in India: Identifying Trade Facilitation related Concerns [PDF]

open access: yes
India has introduced several trade facilitation related measures in the last couple of years. The pro-active strategy adopted by the Central Board of Excise and Customs (CBEC) has helped in introducing several policy measures which have not only ...
Sachin Chaturvedi
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Trade Facilitation in Developing Countries [PDF]

open access: yes
Measures to actively facilitate trade are increasingly seen as essential to assist developing countries in expanding trade and benefiting from globalisation.
Chris Milner   +2 more
core  

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