Results 171 to 180 of about 220,539 (317)

Facilitating the future [PDF]

Nature, 2008
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Barriers and facilitators to pre-exposure prophylaxis uptake among high-risk women and men who have sex with men in Georgia: A pre-implementation mixed-methods study using nominal group technique and the COM-B model. [PDF]

PLOS Glob Public Health
Mgebrishvili T, Kirtadze I, Otiashvili D, Sherozia M, Oliveros D, Altice FL.   +5 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Barriers and Facilitators to ICU Liberation Bundle Implementation and Compliance. [PDF]

Crit Care Explor
Gurnani PK, Setliff EL, Abu-Sultaneh S, Kordik C, Fistler CR, Guo L, Chen X, Dickinson S, Chen P, Bhavani SV, Boncyk C, Barr J.   +11 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Perceived Barriers and Facilitators of Behavioral-Health Modality Change Adoption During the COVID-19 Pandemic: A Systematic Review

Nicholas Sims-Rhodes,1,2 Hannah E Cornwell,1 Emily Barena,3 Vandy Dubre,4 Kimberly S Elliott,5 Eman H Nabulsi,2 Nelly Yuen,3 Sarah M Sass,3 Anastasia Miller,6 Yordanos M Tiruneh,7 Karan P Singh1 1Department of Epidemiology and Biostatistics, University ...
Dubre V, Elliott KS, Tiruneh YM, Cornwell HE, Sims-Rhodes N, Sass SM, Yuen N, Singh KP, Nabulsi EH, Barena E, Miller A   +10 more
core  

Text messaging to support off-campus clinical facilitators of undergraduate student nurses

, 2013
Managing large cohorts of undergraduate student nurses during off-campus clinical placement is complex and challenging. Clinical facilitators are required to support and assess nursing students during clinical placement.
Fox, Amanda, Howard, Christine, Coyer, Fiona   +2 more
core  

Who is left out? A systematic review on the barriers and facilitators for screening participation reported by people in vulnerable situations with strategies for the future. [PDF]

Public Health Pract (Oxf)
van der Kamp J, Krabbenborg L, Kieneker LM, de Winter AF.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source