Results 161 to 170 of about 274,220 (302)

Facilitating the future [PDF]

Nature, 2008
openaire   +2 more sources

Fidelity of Mindfulness Training and Delivery for Adolescent Mental and Metabolic Health. [PDF]

Mindfulness (N Y)
Perzow SED, Chen M, Bothwell S, Gulley LD, Lucas-Thompson RG, Pyle L, Thompson T, Sanchez N, Estrada DE, Tanofsky-Kraff M, Kelsey MK, Mackey ER, Shomaker LB.   +12 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Facilitators' champion behaviors for delivering an evidence-based parenting program. [PDF]

Am J Community Psychol
Lotto CR, Altafim ERP, McCoy DC, Linhares MBM.   +3 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Facilitators and barriers to adventurous play in British preschool-aged children: cross-sectional findings from the British Preschool Children's Play Survey. [PDF]

BMJ Public Health
Rance T, Oliver B, Dodd HF, Hesketh KR.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Perceived Barriers and Facilitators of Behavioral-Health Modality Change Adoption During the COVID-19 Pandemic: A Systematic Review [PDF]

Nicholas Sims-Rhodes,1,2 Hannah E Cornwell,1 Emily Barena,3 Vandy Dubre,4 Kimberly S Elliott,5 Eman H Nabulsi,2 Nelly Yuen,3 Sarah M Sass,3 Anastasia Miller,6 Yordanos M Tiruneh,7 Karan P Singh1 1Department of Epidemiology and Biostatistics, University ...
Dubre V, Elliott KS, Tiruneh YM, Cornwell HE, Sims-Rhodes N, Sass SM, Yuen N, Singh KP, Nabulsi EH, Barena E, Miller A   +10 more
core  

Barriers and Facilitators to Timely Detection and Optimal Management of Chronic Wet Cough in Aboriginal Children Across Australia From the Perspective of Health Care Providers: A Qualitative Study. [PDF]

Med J Aust
Lau GTY, Laird P, Aitken R, Barwick M, Bedford L, Bowden ER, Dalton C, Everingham J, Fuery A, Griffin R, Jain N, Kinghorn M, Knapp R, McCallum GB, Morris P, Norman R, Richmond PC, Saiganesh A, Sibosado S, Toombs M, Walker R, Wilson J, Chang AB, Schultz A.   +23 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source