Results 91 to 100 of about 4,288,907 (276)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Librarian’s Attitude Towards Information Communication Technology in Colleges Affiliated to Sant Gadge Baba Amravati University: A Study [PDF]
, 2013 Now a day’s libraries have deployed the ICT facilities, along with high speed internet connectivity,photo- copiers, and soft copy drop facilities via USB drives, DVD R-W, micro SD drives, fax,scanners and computers. When all such facilities are backed by
Kuralkar, R., Sakarkar, Sachin.
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Mammography facilities serving vulnerable women have longer follow-up times. [PDF]
, 2019 ObjectiveTo investigate mammography facilities' follow-up times, population vulnerability, system-based processes, and association with cancer stage at diagnosis.Data sourcesProspectively collected from San Francisco Mammography Registry (SFMR) 2005-2011,
Kaplan, Celia +3 more
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Technology as tool to overcome barriers of using fitness facilities: A health behavioural perspective [PDF]
, 2019 Underlying health conditions have been highlighted throughout the literature preventing several populations from engaging in physical activity. There have been little to no attempts made in addressing these populations directly in fitness facilities or ...
Cresswell, Montana, Mohamad, Mostafa
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Georgia's Healthcare Inventory for the Elderly [PDF]
, 2005 This fiscal impact presents a summary of the current status of elder-care facilities and programs to provide a baseline for analyses of future pressures on healthcare facilities and programs for the elderly in ...
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
THE RECOVERING OF THE FINANCES BY THE STATE BUDGET [PDF]
Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2006 In this paper is presented a case study realized on an enterprise which has debts to the state budget. The scope of this paper is to show how the State is able to collect its finances from the economic agents more efficient and the economic agents have ...
Nicoleta BARBUTA-MISU
doaj