Results 81 to 90 of about 4,288,907 (276)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Communal residential laundry washing and drying : can it provide demand-side electrical load flexibility? [PDF]
, 2011 Changes in lifestyle have led to increased use and ownership rates of domestic appliances resulting in increasing electrical consumption in the residential sector. An important element of this consumption is due to domestic washing and drying of laundry.
Borg, Simon Paul +5 more
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Facilities ensure sustainability in golf clubs in Gauteng. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2016 The visual aspects of the golf club facilities should create a desire in guests to return. The facilities of any hospitality establishment are referred to as the unrecognised champion that silently welcomes the guest to an area of comfort and safety. But
Mrs E. A. Sao Joao +2 more
doaj
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Educational building conditions and the health of users
Construction Economics and Building, 2016 In order to maintain a healthy learning environment, diagnosis and management of defects in the educational facility are paramount. The preliminary results of the ongoing research reported here seek to identify defects associated with educational ...
Abiodun Olatunji Abisuga +2 more
doaj +1 more source
The EUROnu Study for Future High Power Neutrino Oscillation Facilities [PDF]
, 2014 The EUROnu project was a 4 year FP7 design study to investigate and compare three possible options for future, high power neutrino oscillation facilities in Europe.
Edgecock, R.
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Lectura de Cifras Socio-Económicas de Milagro Retroalimentando la información actual
Ciencia UNEMI, 2011 There are many challenges that businesses have to overcome to satisfy their consumers or attract new customers. Therefore it is necessary to develop profiles to identify factors affecting current and future demand.
Serrano-Mantilla, Gonzalo
doaj
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source