Results 51 to 60 of about 710,173 (345)

Design and Construction of a Radiochemistry Laboratory and cGMP-Compliant Radiopharmacy Facility

Pharmaceuticals
The establishment of a compliant radiopharmacy facility within a university setting is crucial for supporting fundamental and preclinical studies, as well as for the production of high-quality radiopharmaceuticals for clinical testing in human protocols ...
Angela Asor, Abdullah Metebi, Kylie Smith, Kurt Last, Elaine Strauss, Jinda Fan   +5 more
doaj   +1 more source

Design and construction of wastewater treatment facilities for small sewerage facilities

Case Studies in Chemical and Environmental Engineering
The study investigated the effectiveness of clarification of domestic wastewater of small sewerage facilities in the suspended bed of activated sludge. The research was conducted in semi-production and production conditions on the example of a small sewerage facility of East Kazakhstan region with discharge into the river Yertis.
Valentina Kolpakova, Yuliya Yeremeyeva, Samal Anapyanova, Michael Shevtsov, Laura Utepbergenova, Gulnara Abdukalikova, Aisulu Abduova, Nursulu Sarypbekova, Zhanbolat Shakhmov   +8 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The use of BIM and TRIZ in the development of organizational and technological models [PDF]

E3S Web of Conferences
Information modeling currently plays an important role in technological processes in the design of design and working documentation and the performance of construction work at the facility at all stages of the life cycle of the facility.
Ksenia Polosina
doaj   +1 more source

Vrishabhavathi Valley Wastewater Treatment Plant System Upgrade [PDF]

, 2017
Sixteen activated sludge tanks, eight secondary clarifiers, and four return pump stations were designed for the Vrishabhavathi Wastewater Treatment plant in Bangalore India.
Chellaram, Vijay, Miller, Christian
core   +1 more source

Automated retrieval of 3D CAD model objects in construction range images [PDF]

, 2008
Automated and robust retrieval of three-dimensional (313) Computer-Aided Design (CAD) objects from laser scanned data would have many potentially valuable applications in construction engineering and management.
Bosche, F., Haas, C. T.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Shelter housing for cats: Practical aspects of design and construction, and adaptation of existing accommodation

Journal of feline medicine and surgery, 2018
Practical relevance: Not every cat shelter will have purpose-built accommodation but housing designed with the basic needs of cats in mind, whether purpose-built or adapted from existing housing, will improve the experience of cats passing through the ...
D. Wagner, K. Hurley, J. Stavisky
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Risk Factors and Effectiveness of Implementing Multi-Construction Projects for Development of Industrial Facility Sector in Indonesia

IJEBD (International Journal of Entrepreneurship and Business Development)
Purpose: Multi-project management of industrial facility construction has high challenges and complexity. Various factors influence the effectiveness and risks of multi-project implementation.
Saut B Siahaan, Sofia W. Alisjahbana, Onnyxiforus Gondokusumo   +2 more
doaj   +1 more source