Results 61 to 70 of about 697,801 (350)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
EPJ Web of Conferences, 2013 The National Atomic Energy Commission of the Argentine Republic is developing a nuclear waste disposal management programme that contemplates the design and construction of a facility for the final disposal of intermediate-level radioactive wastes.
Schulz F.M. +3 more
doaj +1 more source
An Approach to the Commercial Production of Highly Active Pharmaceutical Ingredients
CHIMIA, 2016 To meet the requirements for production of highly active pharmaceutical ingredients (API) new approaches and technical solutions are required. Prior to the design and construction of a new multipurpose manufacturing facility, a process study was
Andreas Beyeler +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A3 Subscale Diffuser Test Article Design [PDF]
, 2009 This paper gives a detailed description of the design of the A3 Subscale Diffuser Test (SDT) Article Design. The subscale diffuser is a geometrically accurate scale model of the A3 altitude rocket facility.
Saunders, G. P.
core +1 more source
Superconducting magnet system for an experimental disk MHD facility [PDF]
, 1991 A predesign of a split-pair magnet for a magnetohydrodynamic (MHD) facility for testing a 10-MW open-cycle disk or a 5-MW closed-cycle disk generator is presented.
Kate, H.H.J. ten +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Sanitary Design and Construction of Food Processing and Handling Facilities
EDIS, 2005 To ensure safe food and adequate sanitation programs, the facility and surroundings in which food processing and handling operations are conducted must be designed and constructed with sanitary design principles in mind.
Ronald H. Schmidt, Daniel J. Erikson
doaj +1 more source
Placial Justice: Restoring Rehabilitation and Correctional Legitimacy Through Architectural Design
SAGE Open, 2020 Efforts to reduce the correction population have taken many forms across the United States, with the redesign of correctional edifices being met with mixed support from stakeholders.
Victor J. St. John
doaj +1 more source
Developing vanadium redox flow technology on a 9-kW 26-kWh industrial scale test facility: Design review and early experiments [PDF]
, 2018 Redox Flow Batteries (RFBs) have a strong potential for future stationary storage, in view of the rapid expansion of renewable energy sources and smart grids.
Alotto, Piergiorgio +3 more
core +1 more source