Results 61 to 70 of about 97,962 (296)
A proposed framework for collaborative design in a Virtual Environment [PDF]
, 2008 This paper describes a proposed framework for a collaborative design in a virtual environment. The framework consists of components that support a true collaborative design in a real-time 3D virtual environment.
Shiratuddin, M.F., Breland, J.
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The design and construction of a shock tube facility [PDF]
, 1965 It is the object of this thesis to give an account of the considerations necessary to design, construct, and operate a shock tube facility. The primary purpose of the facility was to provide a means to study high strength shock waves in physics ...
Crede, William Adolph
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Sanitary Design and Construction of Food Processing and Handling Facilities
EDIS, 2005 To ensure safe food and adequate sanitation programs, the facility and surroundings in which food processing and handling operations are conducted must be designed and constructed with sanitary design principles in mind.
Ronald H. Schmidt, Daniel J. Erikson
doaj +1 more source
Placial Justice: Restoring Rehabilitation and Correctional Legitimacy Through Architectural Design
SAGE Open, 2020 Efforts to reduce the correction population have taken many forms across the United States, with the redesign of correctional edifices being met with mixed support from stakeholders.
Victor J. St. John
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Virtual Design and Construction
, 2009 Presented on August 31, 2009 from 6 to 8 pm in the East Architecture Auditorium on the Georgia Tech Campus.Martin Fischer leads the world’s premier academic research center for virtual design and construction of architecture/engineering/construction ...
Fischer, Martin
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Genetic search for solving construction site-level unequal-area facility layout problems
, 2000 A construction site represents a conflux of concerns, constantly calling for a broad and multi-criteria approach to solving problems related to site planning and design.
Li, H, H. Li, P. Love, Love, PED
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source