Results 141 to 150 of about 3,593,801 (351)

Extensions to emergency vehicle location models [PDF]

open access: yes, 2003
This paper is concerned with extending models for the Maximal Covering Location Problem in two ways. First, the usual 0-1 coverage definition is replaced by the probability of covering a demand within the target time.
Rand, G K, Alsalloum, O I
core  

SONG: A Multi-Objective Evolutionary Algorithm for Delay and Energy Aware Facility Location in Vehicular Fog Networks. [PDF]

open access: yesSensors (Basel), 2023
Hussain MM   +7 more
europepmc   +1 more source

Reliable Emergency Facility Location Planning Under Complex Polygonal Barriers and Facility Failure Risks

open access: yesMathematical and Computational Applications
Emergency facility location and layout are critical to the efficiency of emergency rescue and resource allocation. However, practical emergency scenarios are plagued by two key challenges: the risk of facility failure due to various uncertain factors and
Mingyuan Liu   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Distribution Network Configuration Considering Inventory Cost [PDF]

open access: yes
Inter-city distribution network structure is considered as one of which determine the quantity of economic activities in each city. In the field of operations research, several types of optimal facility location problem and algorithms for them have been ...
Makoto Okumura, Makoto Tsukai
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Fractional location problems

open access: yes
In this paper we analyze some variants of the classical uncapacitated facility location problem with a ratio as an objective function. Using basic concepts and results of fractional programming, we identify a class of one-level fractional location ...
Frenk, J.B.G.   +2 more
core  

LUTI models, freight transport and freight facility location [PDF]

open access: yes, 2016
The subject of this book is the new scientific research in the field of modelling the interaction between land use and transport (LUTI modelling). Transport and the location of activities in space have been important themes of study in engineering ...
Nuzzolo, A., Comi, A., Papa, E.
core  

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