Results 131 to 140 of about 3,593,801 (351)
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Locating emergency services with priority rules: The priority queuing covering location problem [PDF]
One of the assumptions of the Capacitated Facility Location Problem (CFLP) is that demand is known and fixed. Most often, this is not the case when managers take some strategic decisions such as locating facilities and assigning demand points to those ...
Francisco Silva, Daniel Serra
core
Nested-Solution Facility Location Models. [PDF]
Optim Lett, 2022 McGarvey RG, Thorsen A.
europepmc +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
This thesis is a critical investigation into the development, application and evaluation of ant colony optimisation metaheuristics, with a view to solving a class of capacitated facility location problems. The study is comprised of three phases.
Venables, Harry
core
Locating Facilities in Uncertainty Conditions based on D Number Theory [PDF]
چشمانداز مدیریت صنعتی, 2016 Organizational senior managers decide about Facility location under uncertainty and lack of enough Information, while the decision is time consuming, scientific and strategic. To select the optimal facility location, scholars have proposed a variety of
Reza Shaikh, Hanieh Shambaiati
doaj
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
A Two-Stage Optimization Approach for Healthcare Facility Location- Allocation Problems With Service Delivering Based on Genetic Algorithm. [PDF]
Int J Public Health, 2023 Salami A, Afshar-Nadjafi B, Amiri M.
europepmc +1 more source
AlgorithmsToday, facility location planning primarily pertains to the long-term strategic and operational decision-making of large public and private organizations, and the significant costs associated with facility location, construction, and operation have ...
Salar Babaei +3 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source