Results 111 to 120 of about 4,534,692 (327)

Facility location based on Adjusted Present Value

open access: yesOperations Research Perspectives
Supply chain network design aims to optimize strategic decisions such as facility location decisions.These decisions have a major impact on the supply chain, but also on the financial value of the company.
Hamidreza Rezaei   +4 more
doaj   +1 more source

Capacitated facility location: Valid inequalities and facets [PDF]

open access: yes
Location Theory;Optimization;Capacity ...
Aardal, K.I., Pochet, Y., Wolsey, L.A.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Emergency facilities location

open access: yesMathematical Modelling, 1986
AbstractThis paper considers the problem of locating two emergency stations in a small township so as to minimize the total response time to all emergencies. This problem was solved by a computer program which determines the response time for all possible solutions and finds the optimal one. The problem was first approached by assuming that emergencies
Goodman, Albert   +3 more
openaire   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

AHP Methodology Application in Garage-parking Facility Location Selection

open access: yesPromet (Zagreb), 2011
The paper deals with the selection of traffic infrastructure facility location by applying the AHP (Analytic Hierarchy Process) multi-criteria analysis methodology.
Aleksandra Deluka-Tibljaš   +2 more
doaj   +1 more source

Online facility location [PDF]

open access: yesProceedings 42nd IEEE Symposium on Foundations of Computer Science, 2001
We consider the online variant of facility location, in which demand points arrive one at a time and we must maintain a set of facilities to service these points. We provide a randomized online O(1)-competitive algorithm in the case where points arrive in random order.
openaire   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Solving a Facility Location Problem by Three Multi-Criteria Decision Making Methods [PDF]

open access: yesInternational Journal of Research in Industrial Engineering, 2014
Selecting the most appropriate and optimal facility location for a new organization or expansion of an existing location is an important strategic issue.
M. Niyazi, R. Tavakkoli-Moghaddam
doaj  

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