Results 101 to 110 of about 4,534,692 (327)
Urban Public Facility Location, Multipurpose Trips and Spatial Competition: equilibrium and welfare analysis [PDF]
We study the impact of the urban location of one single public facility on spatial competition ` la Hotelling. If transportation costs are very low compared to the value of the public service then both firms tacitly choose the facility location without ...
Baudewyns
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Aceh International Journal of Science and Technology, 2013 -This paper presents model of Indonesian LPG supply chain by opening new facilities (new echelon) taking into account the current facilities. The objective is to investigate the relation between distribution costs such as transportation, inventory cost ...
Ilyas Masudin
doaj +1 more source
The capacitated mobile facility location problem
European Journal of Operational Research, 2019 The capacitated mobile facility location problem (CMFLP) arises in logistics planning of community outreach programs delivered via mobile facilities. It adds capacity restrictions to the mobile facility location problem introduced previously by Demaine ...
S. Raghavan, M. Sahin, F. Salman
semanticscholar +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A new approximation algorithm for the multilevel facility location problem [PDF]
, 2007 In this paper we propose a new integer programming formulation for the multi-level facility location problem and a novel 3-approximation algorithm based on LP rounding. The linear program we are using has a polynomial number of variables and constraints,
Gabor, Adriana F. +1 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Nearly Linear-Work Algorithms for Mixed Packing/Covering and Facility-Location Linear Programs
, 2014 We describe the first nearly linear-time approximation algorithms for explicitly given mixed packing/covering linear programs, and for (non-metric) fractional facility location.
Young, Neal E.
core
Facility location on terrains [PDF]
, 2001 Given a terrain defined as a piecewise-linear function with n triangles, and m point sites on it, we would like to identify the location on the terrain that minimizes the maximum distance to the sites.
Aronov, B. +3 more
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source