Results 151 to 160 of about 3,593,801 (351)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Convalescent plasma bank facility location-allocation problem for COVID-19. [PDF]

open access: yesTransp Res E Logist Transp Rev, 2021
Manupati VK   +5 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A Pure Binary LP Model to the Facility Layout Problem [PDF]

open access: yes
In facility layout problems, a major concern is the optimal design or remodeling of the facilities of an organization. The decision maker’s objective is to arrange the facility in an optimal way, so that the interaction among functions (i.e.
Papahristodoulou, Christos
core  

Lower-bounded facility location

open access: yes, 2010
We study the lower-bounded facility location problem which generalizes the classical uncapacitated facility location problem in that it comes with lower bound constraints for the number of clients assigned to a facility in the case that this facility is ...
Zoya Svitkina
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Heuristic Methods Based on MINLP Formulation for Reliable Capacitated Facility Location Problems

open access: yesInternational Journal of Industrial Engineering and Production Research, 2015
This paper addresses a reliable facility location problem with considering facility capacity constraints. In reliable facility location problem some facilities may become unavailable from time to time.
Mohammad Rohaninejad   +2 more
doaj  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy