Results 51 to 60 of about 3,593,801 (351)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Journal of Lipid ResearchLipids play pivotal roles in an extensive range of metabolic and physiological processes. In recent years, the convergence of trapped ion mobility spectrometry and MS has enabled 4D-lipidomics, a highly promising technology for comprehensive lipid ...
Yorrick R.J. Jaspers +12 more
doaj +1 more source
Parallel Optimization Algorithm for Competitive Facility Location
Mathematical Modelling and Analysis, 2015 A stochastic search optimization algorithm is developed and applied to solve a bi-objective competitive facility location problem for firm expansion.
Algirdas Lančinskas +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
Facility Location Problems: Models, Techniques, and Applications in Waste Management
Recycling, 2020 This paper presents a brief description of some existing models of facility location problems (FLPs) in solid waste management. The study provides salient information on commonly used distance functions in location models along with their corresponding ...
O. J. Adeleke, D. Olukanni
semanticscholar +1 more source
Competitive Facility Location with Competition of Customers
, 2015 The research work dealing with the competitive location problems is limited only to the competition among the locators, that is, it is supposed that either both the locator and the allocator are the same or the customer knows the optimality criterion of ...
Athanasia Karakitsiou +1 more
core +1 more source
A Dynamic Framework for Community-Facility Siting with Inter-Community Competition
Applied SciencesLocating community facilities is a long-term, daunting task for governments, requiring ongoing budget or policy updates for gradual improvement. This study proposes a bi-objective multi-scenario dynamic model (BOMSDM) for community-facility siting, which
Sisi Zhu, Haoying Han, Anran Dai
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
A two-stage robust model for a reliable p-center facility location problem
Applied Mathematical Modelling, 2020 We propose a two-stage robust model for reliable facility location when some facilities can be disrupted, for instance by a natural disaster. A reliable network is designed in a “proactive” planning phase, and when a facility is disrupted, its original ...
B. Du, Hong Zhou, R. Leus
semanticscholar +1 more source
A Hybrid Approach for The Design of Facility Location and Supply Chain Network Under Supply and Demand Uncertainty: A Systematic Review [PDF]
, 2009 In today’s extremely competitive marketplace, firms are facing the need to meet or exceed increasing customer expectations while cutting costs to stay competitive in a global market. To develop competitive advantage in this business climate, companies
Meeyai, Sutthipong
core