Results 51 to 60 of about 4,534,692 (327)
Parallel Optimization Algorithm for Competitive Facility Location
A stochastic search optimization algorithm is developed and applied to solve a bi-objective competitive facility location problem for firm expansion.
Algirdas Lančinskas +2 more
doaj +1 more source
Locating a bioenergy facility using a hybrid optimization method [PDF]
In this paper, the optimum location of a bioenergy generation facility for district energy applications is sought. A bioenergy facility usually belongs to a wider system, therefore a holistic approach is adopted to define the location that optimizes the ...
Rentizelas, Athanasios A. +1 more
core +1 more source
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
wiley +1 more source
A Dynamic Framework for Community-Facility Siting with Inter-Community Competition
Locating community facilities is a long-term, daunting task for governments, requiring ongoing budget or policy updates for gradual improvement. This study proposes a bi-objective multi-scenario dynamic model (BOMSDM) for community-facility siting, which
Sisi Zhu, Haoying Han, Anran Dai
doaj +1 more source
Scalable Facility Location for Massive Graphs on Pregel-like Systems [PDF]
We propose a new scalable algorithm for facility location. Facility location is a classic problem, where the goal is to select a subset of facilities to open, from a set of candidate facilities F , in order to serve a set of clients C.
Aristides Gionis +4 more
core +1 more source
Predicting Optimal Facility Location without Customer Locations [PDF]
Deriving meaningful insights from location data helps businesses make better decisions. One critical decision made by a business is choosing a location for its new facility. Optimal location queries ask for a location to build a new facility that optimizes an objective function.
Yilmaz, Emre +2 more
openaire +3 more sources
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Facility location models are well established in various application areas with more than a century of history in academia. Since the 1970s the trend has been shifting from manufacturing to service industries.
R. Farahani +4 more
semanticscholar +1 more source
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee +9 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

