Results 71 to 80 of about 4,534,692 (327)

Robust Facility Location Problem for Bio-waste Transportation

open access: yesChemical Engineering Transactions, 2017
The article presents an optimisation tool for bio-waste facility allocation. The quantity of bio-waste produced in individual territorial units is a key factor for the selection of localities when constructing a new facility. Bio-waste production changes
D. Hrabec   +5 more
doaj   +1 more source

Red–Blue k-Center Clustering with Distance Constraints

open access: yesMathematics, 2023
We consider a variant of the k-center clustering problem in IRd, where the centers can be divided into two subsets—one, the red centers of size p, and the other, the blue centers of size q, such that p+q=k, and each red center and each blue center must ...
Marzieh Eskandari   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Undesirable Facility Location under Uncertainty: Modeling and Algorithm [PDF]

open access: yesمدیریت تولید و عملیات, 2019
: In undesirable facility location problem contrary to desirable location, facilities are located far from service receiver facilities as much as possible. The problem of locating such facilities is discussed in this study.
Parisima Pakravan, Javad Behnamian
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A New Type of Chronic Wound Infection after Wisdom Tooth Extraction: A Diagnostic Approach with 16S-rRNA Gene Analysis, Next-Generation Sequencing, and Bioinformatics

open access: yesPathogens, 2020
Delayed-onset infections are rare postoperative complications of lower third molar extractions. This article presents a case of a chronic combined hard and soft tissue infection after the extraction of a third molar, where the causative organisms could ...
Sebastian Böttger   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Boolean facility location problem with client preferences

open access: yesНауковий вісник Ужгородського університету. Серія: Математика і інформатика, 2018
Boolean facility location problem with client preferences is considered. Mathematical model of the problem is built. Branchs and bounds  method to solve the problem is proposed. The lower bound calculation method as the solution of the linear programming
Ю. В. Андрашко   +1 more
doaj   +1 more source

Clustering based hybrid approach for facility location problem [PDF]

open access: yesManagement Science Letters, 2017
The main objective of facility location problem is the utilization of the facility by maximum number of possible customers so that the profit is maximized.
Ashish Sharma   +2 more
doaj   +1 more source

A Survey on Approximation Mechanism Design without Money for Facility Games

open access: yes, 2015
In a facility game one or more facilities are placed in a metric space to serve a set of selfish agents whose addresses are their private information. In a classical facility game, each agent wants to be as close to a facility as possible, and the cost ...
A. Tamir   +17 more
core   +1 more source

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