Results 61 to 70 of about 3,593,801 (351)
Memoryless facility location in one pass
, 2011 We present the first one-pass memoryless algorithm for metric Facility Location that maintains a set of facilities approximating the optimal facility configuration within a constant factor.
Fotakis, D, Dimitris Fotakis
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
European Journal of Operational Research, 2019 Facility location models are well established in various application areas with more than a century of history in academia. Since the 1970s the trend has been shifting from manufacturing to service industries.
R. Farahani +4 more
semanticscholar +1 more source
Incremental algorithms for Facility Location and k-Median
, 2006 In the incremental versions of Facility Location and k-Median, the demand points arrive one at a time and the algorithm maintains a good solution by either adding each new demand to an existing cluster or placing it in a new singleton cluster.
Fotakis, Dimitris +2 more
core +1 more source
A Survey of Approximation Algorithms for the Universal Facility Location Problem
MathematicsThe facility location problem is a classical combinatorial optimization problem with extensive applications spanning communication technology, economic management, traffic governance, and public services.
Hanyin Xiao +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fast bounding procedures for large instances of the simple plant location problem [PDF]
, 2012 Some new, simple and extremely fast bounding procedures are presented for large-scale instances of the Simple Plant Location Problem. The lower-bounding procedures are based on dual ascent.
Miller, Sebastian John +3 more
core +1 more source
Optimal Location of an Oil Storage Facility
Undergraduate Journal of Mathematical Modeling: One + Two, 2010 Given three oil drilling sites, we devise a method to determine the optimal location for a storage facility such that the total length of pipeline required to connect each site to the facility is minimized. First we represent the total distance of piping
Giovanni Quiel
doaj +1 more source