Results 21 to 30 of about 35,394 (228)

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

Acta Neuropathologica Communications, 2022
The Bridging Integrator 1 (BIN1) gene is a major susceptibility gene for Alzheimer’s disease (AD). Deciphering its pathophysiological role is challenging due to its numerous isoforms.
Erwan Lambert, Orthis Saha, Bruna Soares Landeira, Ana Raquel Melo de Farias, Xavier Hermant, Arnaud Carrier, Alexandre Pelletier, Johanna Gadaut, Lindsay Davoine, Cloé Dupont, Philippe Amouyel, Amélie Bonnefond, Frank Lafont, Farida Abdelfettah, Patrik Verstreken, Julien Chapuis, Nicolas Barois, Fabien Delahaye, Bart Dermaut, Jean-Charles Lambert, Marcos R. Costa, Pierre Dourlen   +21 more
doaj   +1 more source

Identification of several eating habits that mediate the association between eating behaviors and the risk of obesity

Obesity Science & Practice, 2022
Objective Eating behaviors play important roles in the development of obesity. A better knowledge of the psychological aspects of eating behaviors in individuals with and without obesity and their consequences on daily eating and lifestyle habits would ...
Estelle Aymes, Gabrielle Lisembard, Jean Dallongeville, Julien Rousseaux, Marie‐Pierre Dumont, Philippe Amouyel, Monique Romon, Aline Meirhaeghe   +7 more
doaj   +1 more source

Identification of patient subtypes based on protein expression for prediction of heart failure after myocardial infarction

iScience, 2023
Summary: This study investigates the ability of high-throughput aptamer-based platform to identify circulating biomarkers able to predict occurrence of heart failure (HF), in blood samples collected during hospitalization of patients suffering from a ...
Wilfried Heyse, Vincent Vandewalle, Guillemette Marot, Philippe Amouyel, Christophe Bauters, Florence Pinet   +5 more
doaj   +1 more source

Mitochondrial-Targeted Therapies Require Mitophagy to Prevent Oxidative Stress Induced by SOD2 Inactivation in Hypertrophied Cardiomyocytes

Antioxidants, 2022
Heart failure, mostly associated with cardiac hypertrophy, is a major cause of illness and death. Oxidative stress causes accumulation of reactive oxygen species (ROS), leading to mitochondrial dysfunction, suggesting that mitochondria-targeted therapies
Victoriane Peugnet, Maggy Chwastyniak, Paul Mulder, Steve Lancel, Laurent Bultot, Natacha Fourny, Edith Renguet, Heiko Bugger, Olivia Beseme, Anne Loyens, Wilfried Heyse, Vincent Richard, Philippe Amouyel, Luc Bertrand, Florence Pinet, Emilie Dubois-Deruy   +15 more
doaj   +1 more source

Une approche centrée sur la personne pour l’analyse des facteurs de stress liés à la pandémie de COVID-19

Promotion de la santé et prévention des maladies chroniques au Canada, 2022
IntroductionLa pandémie de COVID­19 et les effets du confinement qui en ont découlé ont eu un effet néfaste sur la situation sociale, professionnelle et financière des individus.
Ann-Renee Blais, Ève-Marie Blouin Hudon, Matthew Lymburner   +2 more
doaj   +1 more source

Le burn-out des enseignants : entre facteurs de risque et facteurs de protection.

Moroccan Journal of Quantitative and Qualitative Research, 2022
Ces dernières années, l’enseignement a subi plusieurs changements qui ont affecté la vie professionnelle des enseignants. En effet, les professeurs sont appelés à s’adapter continuellement à l’évolution de la société.
Houda ELAICHE
doaj   +1 more source

Projet GESSICa - Facteurs de risque environnementaux et inégalités sociales associés aux cancers en Guadeloupe

, 2022
Le projet " GESSICa " (Facteurs de risque environnementaux et inégalités sociales associés aux cancers en Guadeloupe) a pour principal objectif d'améliorer la surveillance et la connaissance des cancers sur le territoire guadeloupéen par une approche ...
Cattan, Philippe, Ducrot, A., Degenne, Pascal, Luce, Danièle, Tran, Annelise, Milard, A., Deloumeaux, Jacqueline, Bonnal, Vincent, Dufleit, Victor, Bhakkan-Mambir, B.   +9 more
core  

Balancing risk and reward—Perceptions of bats and their ecological role in Reunion island

People and Nature, EarlyView.
Abstract Context: Bats provide vital ecosystem services but can also generate disservices or sanitary concerns, particularly where human–bat interactions are frequent. Understanding public perceptions of bats is essential for effective conservation and risk communication.
Rachel Leong, Anne Atlan, Camille Lebarbenchon   +2 more
wiley   +1 more source

Caractéristiques communes, facteurs de risque et facteurs de protection chez les adolescents auteurs d’abus sexuels [PDF]

, 2016
Rapport de stage présenté à la Faculté des Études Supérieures des arts et sciences, Département de criminologie, en vue de l’obtention du grade de Maîtrise (M. Sc.) en criminologie, option interventionDans une optique de criminologie développementale, la
Demay, Vanessa Sandra
core   +2 more sources

The birth of an earth being: ‘Rights of nature’ in Brazilian Amazonia and elsewhere Naissance d'un être de la terre : « droits de la nature » en Amazonie brésilienne et ailleurs

Journal of the Royal Anthropological Institute, EarlyView.
In June 2023, the Laje River, located in the traditional territory of the Wari’ Indigenous people in Rondônia, Brazil, was declared a legal entity, an earth being, with rights, following the co‐ordinated action of an indigenous councillor and non‐indigenous activists.
Aparecida Vilaça
wiley   +1 more source