Results 261 to 270 of about 20,236,854 (354)

Health Behavior of Young People Aged 12-18 with Autism Spectrum Disorder and Intellectual Disabilities in Hungary. [PDF]

Children (Basel)
Barabás Á, Erdei RJ, Móré M, Pázmány V, Sárváry A, Toldy-Schedel E, Grestyák AM, Nagy AC, Kiss OP, Takács P.   +9 more
europepmc   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Aging dimensions and markers as relative predictors of mortality in a longitudinal epidemiological sample. [PDF]

PLoS One
Markon KE, Mann FD, Freilich CD, Cole S, Krueger RF.   +4 more
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Evaluation scale and behavioral model construction for intention to use postpartum exercise rehabilitation mobile application based on user experience. [PDF]

Front Psychol
Wang Z, Wang Z, Deng R, Xia M, Huang L.
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Analysis of the Internal Structure and Psychometric Properties of the Entrapment Scale in Spanish Adolescents and Emerging Adults. [PDF]

Eur J Investig Health Psychol Educ
Huertes-Del Arco A, Izquierdo-Sotorrío E, Ramírez-Uclés I, Carrasco MA, Holgado-Tello FP.   +4 more
europepmc   +1 more source

Factors responsible for the sex expression of Japanese cucumber VI.

, 1957
H. Ito, Takashi Saito
openalex   +2 more sources

Gang-involved young people: custody and beyond: a practitioner’s guide [PDF]

, 2015
Bateman, T, Factor, F, Goodfellow, P, Pitts, J   +3 more
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