Results 121 to 130 of about 3,317,431 (294)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Food education: factors involved in food selection

open access: yesInternational Journal of Social and Educational Innovation, 2017
There are many factors influencing a food product selection, even if the most known is health benefits. This study describes the effect size of nine factors such as health, mood, convenience, sensory quality, ingredients, price, energetic value ...
Madalina Iuga
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Visualizing exploratory factor analysis models [PDF]

open access: yes
Exploratory factor analysis (EFA) is an important tool in data analyses, particularly in social science. Usually four steps are carried out which contain a large number of options.
Cornelia Wagner, Sigbert Klinke
core  

Anterior Knee Pain Scale (AKPS): structural and criterion validity in Brazilian population with patellofemoral pain

open access: yesBMC Musculoskeletal Disorders
Purpose To identify the best internal structure of the Brazilian version of the Anterior Knee Pain Scale (AKPS), comparing different instrument structures (structural validity) and correlating the scores of the versions (criterion validity).
Francisco Basilio da Silva-Júnior   +9 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A FACTOR ANALYSIS OF SUPERMARKET MANAGEMENT PRACTICES

open access: yes
Empirically based management practice indices are constructed using results from factor analysis of data from 344 stores in the 2000 Supermarket Panel. These indices are compared to six management indices based on expert opinion.
King, Robert P., Jacobson, Elaine M.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Sensitivity analysis and related analysis: A survey of statistical techniques

open access: yes
This paper reviews the state of the art in five related types of analysis, namely (i) sensitivity or what-if analysis, (ii) uncertainty or risk analysis, (iii) screening, (iv) validation, and (v) optimization. The main question is: when should which type
Kleijnen, J.P.C.
core  

Structural equation modeling in epidemiology

open access: yesCadernos de Saúde Pública
Structural equation modeling (SEM) is an important statistical tool for evaluating complex relations in several research areas. In epidemiology, the use and discussion of SEM have been limited thus far. This article presents basic principles and concepts
Leila Denise Alves Ferreira Amorim   +10 more
doaj  

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