Results 131 to 140 of about 3,241,957 (247)

Cross-cultural adaptation and psychometric evaluation of the dengue preventive attitudes questionnaire for Indonesian public health nurses. [PDF]

BMC Nurs
Hertanti NS, Chuang YH.
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Methods for analytical validation of novel digital clinical measures: A simulation study. [PDF]

PLoS One
Turner S, Chen C, Acosta R, Chon R, Daza EJ, Floden L, Langford J, Simmatis L, Terluin B, Vandendriessche B, Fromy P.   +10 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Prognostic factor research: why it matters in orthopaedics and how we do it better. [PDF]

Bone Jt Open
Hamoodi ZA, Riley RD, Collins GS, Kearsley-Fleet L, Sergeant JC, Watts AC.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Análisis estadístico implicativo para la identificación de factores pronósticos de la mortalidad por cáncer de mama

Medisan
Se realizó un estudio observacional y analítico para evaluar la utilidad de una nueva técnica de análisis estadístico implicativo en la identificación de los factores pronósticos de la mortalidad por cáncer de mama en la provincia de Santiago de Cuba ...
Alina Moraga Rodríguez, Larisa Zamora Matamoros, Nelsa M Sagaró del Campo, Annia Moraga Rodríguez, Alina Rodríguez Griñán   +4 more
doaj  

Refinement and Preliminary Validation of the Technological Competency as Caring in Healthcare Instrument (TCCHI): Psychometric Evaluation of a Concise Three-Factor Model. [PDF]

Healthcare (Basel)
Yamanaka R, Ito H, Takashima Y, Soriano K, Onishi K, Betriana F, Soriano GP, Blaquera AP, Akiyama T, Tanioka R, Kwan RYC, Viernes JB, Miyagawa M, Osaka K, Yasuhara Y, Akaike M, Tanioka T.   +16 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source