Results 201 to 210 of about 3,123,421 (247)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

A Study on the Validity and Reliability of the Turkish Translation of the Self-Report Wender-Reimherr Adult Attention Deficit Disorder Scale. [PDF]

Int J Methods Psychiatr Res
Karakaya S, Ertekin İA, Çolak B, Öncü B.   +3 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

BACH1-mediated transcriptional repression of pro-angiogenic factors drives angiogenic impairment in hypertension. [PDF]

Front Cardiovasc Med
Gao D, Wu Z, Zhou Z, Liang J.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Chromatin Remodeling Factor Arp8 Is Involved in the Regulation of Aflatoxin Biosynthesis and Fungal Pathogenicity of <i>Aspergillus flavus</i>. [PDF]

J Fungi (Basel)
Ma D, Yao Y, Luo W, Wang P, Wu D, Yang Y, Ye K, Hu Y, Gao Y, Sun M, Zhang C, Chen L, Chen X, Zhuang Z.   +13 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Comparative risk of <i>Clostridioides difficile</i> infection in patients with Crohn's disease receiving ustekinumab versus anti-TNF therapy: a retrospective cohort study. [PDF]

Therap Adv Gastroenterol
Huang J, Zhang M, Deng J, Yao J, Peng X, Zhang Q, Zhi M, Liu T.   +7 more
europepmc   +1 more source

Macrophage <i>Mtdh</i> deficiency discordantly regulated tumor growth and metastasis through increased thrombospondin-1 production. [PDF]

J Immunother Cancer
Jiang Y, Min L, Yang X, Zhang F, Sun Q, Lin Y, Zhang W, Li Y, Fu G, Liu X.   +9 more
europepmc   +1 more source

HOXB8 promotes invasion and metastasis of high-grade serous ovarian cancer via suppression of the KDM6B/C/EBPα signaling axis. [PDF]

Transl Cancer Res
Xiang L, Lou Y, Wang P, Hu Y, Wang D.
europepmc   +1 more source