Mrs. J. A. Naismith dies, 1937
A small newspaper clipping under the head of "Mrs. J. A. Naismith: Wife of Inventor of Basketball Played on First Girl's Team" that talks about the death of Maude Naismith, wife of Dr. James Naismith the inventor of basketball, from heart disease. It was
Associated Press;
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Clinical Images: Rapidly progressive granulocyte colony-stimulating factor-associated arteritis: initial normal imaging as a diagnostic pitfall. [PDF]
Kayabe Kuroda C +7 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The seminal plasma sTLR4/IL-1β ratio as an independent factor associated with sperm chromatin condensation defects. [PDF]
Zhao Y +8 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Includes the Constructor annual, v. 1-2, issued in lieu of the Mar. issues for 1969-1970.Vol. 4-11, no. 4, 1922-Apr. 1929 called new series, cf. Union list of serials.Mode of access: Internet.Official publication of the Associated General Contractors of ...
Associated General Contractors of America.
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Gut Microbiome as a Lifestyle Risk Factor Associated with Prostate Cancer. [PDF]
Liss MA +8 more
europepmc +1 more source

