Results 111 to 120 of about 11,313,113 (356)
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
Short-time height distribution in 1d KPZ equation: starting from a parabola
We study the probability distribution $\mathcal{P}(H,t,L)$ of the surface height $h(x=0,t)=H$ in the Kardar-Parisi-Zhang (KPZ) equation in $1+1$ dimension when starting from a parabolic interface, $h(x,t=0)=x^2/L$. The limits of $L\to\infty$ and $L\to 0$
Kamenev, Alex+2 more
core +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
This editorial describes the process of periodic evaluation by CAPES, based on commercial indices proposed by companies such as the ISI FI by Thomson Reuters and SCImago by Scopus and public indices as proposed by SciELO and other freely calculated ...
Nelson Wellausen Dias+1 more
doaj +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
The complement system is a first line of defence against infectious, tumoral or autoimmune processes, and it is constitutively regulated to avoid excessive or unspecific activation. Factor H (FH), a most relevant complement regulator, controls complement
Irene Gómez Delgado+1 more
doaj
Staircase palindromic polynomials [PDF]
We study a class of monic-palindromic polynomials that we call staircase palindromic polynomials. Specifically, suppose $S(x, n, h)$ is a polynomial of degree n with the special form: $S(x; n; h) = x^n + 2x^{n-1} + 3x^{n-2} + \dots + (h - 1)x^{n-h+2} + hx^{n-h+1} + \dots + hx^{h-1} + (h - 1)x^{h-2} + \dots + 2x + 1$.
arxiv
AbstractGiven a fixed small graph H and a larger graph G, an H-factor is a collection of vertex-disjoint subgraphs $H'\subset G$, each isomorphic to H, that cover the vertices of G. If G is the complete graph $K_n$ equipped with independent U(0,1) edge weights, what is the lowest total weight of an H-factor?
Joel Larsson Danielsson+1 more
openaire +2 more sources