Results 131 to 140 of about 3,567,577 (243)

Dual Role of Factor H-Related Protein 1 in IgA Nephropathy Kidney Injury. [PDF]

Kidney Int Rep
Kang Y, Li X, Yuan X, Shi S, Lv J, Zhu L, Zhang H.   +6 more
europepmc   +1 more source

The Central Portion of Factor H (Modules 10–15) Is Compact and Contains a Structurally Deviant CCP Module

, 2009
Christoph Q. Schmidt, Andrew P. Herbert, Haydyn D. T. Mertens, Mara Guariento, Dinesh C. Soares, Dušan Uhrı́n, Arthur J. Rowe, Dmitri I. Svergun, Paul N. Barlow   +8 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Structure-function of recombinant Na/H exchanger regulatory factor (NHE-RF). [PDF]

, 1998
E. J. Weinman, Deborah Steplock, K. Tate, Randy A. Hall, Robert F. Spurney, Shirish Shenolikar   +5 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Gene and protein profiling of Dickkopf-3 and complement factor H in periodontitis and coronary artery disease. [PDF]

Front Dent Med
Mahendra J, Maharavi B, Natarajan PM, Arumugam M.   +3 more
europepmc   +1 more source

Bacterial Factors Other Than Injected CagA and Those Mediating IL-8 Induction Participate in H. pylori -Mediated Gastric H,K-ATPase Repression

, 2011
Yongmei Zhang, Charles E. Hammond, Richard M. Peek, Steffen Backert, Adam J. Smolka   +4 more
openalex   +1 more source

Association of Complement Factor D and H Polymorphisms with Recurrent Pregnancy Loss [PDF]

, 2019
Hee Young Cho, Han Sung Park, Eun Ju Ko, Chang Soo Ryu, Jung Oh Kim, Young Ran Kim, Eun Hee Ahn, Woo Sik Lee, Nam Keun Kim   +8 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Complement therapeutic factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infections. [PDF]

J Immunol
McKaig CW, Malfetano J, Tran Y, Yang X, Pal U, Wycoff K, Lin YP.   +6 more
europepmc   +1 more source