Results 61 to 70 of about 36,394,742 (371)

Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies

Frontiers in Immunology, 2021
Complement dysregulation is characteristic of the renal diseases atypical hemolytic uremic syndrome (aHUS) and complement component 3 glomerulopathy (C3G).
Markus A. Loeven, Marissa L. Maciej-Hulme, Cansu Yanginlar, Melanie C. Hubers, Edwin Kellenbach, Mark de Graaf, Toin H. van Kuppevelt, Jack Wetzels, Ton J. Rabelink, Richard J. H. Smith, Johan van der Vlag   +10 more
doaj   +1 more source

Regulation of age-related macular degeneration-like pathology by complement factor H

Proceedings of the National Academy of Sciences of the United States of America, 2015
Significance Age-related macular degeneration (AMD) affects approximately one-third of Americans over 70 and is characterized by lipoprotein-rich sub-retinal pigmented epithelium (sub-RPE) deposits.
C. Toomey, Una Kelly, D. Saban, Catherine Bowes Rickman   +3 more
semanticscholar   +1 more source

Semisimple Hopf actions on Weyl algebras [PDF]

, 2014
We study actions of semisimple Hopf algebras H on Weyl algebras A over a field of characteristic zero. We show that the action of H on A must factor through a group algebra; in other words, if H acts inner faithfully on A, then H is cocommutative.
Cuadra, Juan, Etingof, Pavel, Walton, Chelsea   +2 more
core   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

Population Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy

Kidney International, 2015
Abnormal regulation of the complement alternative pathway is associated with C3 glomerulopathy. Complement factor H is the main plasma regulator of the alternative pathway and consists of 20 short consensus repeat (SCR) domains. Although recombinant full-
Eva-Maria Nichols, T. Barbour, I. Pappworth, E. Wong, J. Palmer, N. Sheerin, M. Pickering, K. Marchbank   +7 more
semanticscholar   +1 more source

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.

PLoS Genetics, 2011
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the ...
Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao   +56 more
doaj   +1 more source

Network topology drives population temporal variability in experimental habitat networks

Population Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu, J. Angus Webb, William D. Bovill, Elise L. King   +3 more
wiley   +1 more source

The Factorization of $H^p$ and the Commutators

Tokyo Journal of Mathematics, 1983
\textit{R. Coifman}, \textit{R. Rochberg} and \textit{G. Weiss} [Ann. Math., II. Ser. 103, 611-635 (1976; Zbl 0326.32011)] and \textit{A. Uchiyama} [Pac. J. Math. 92, 453-468 (1981; Zbl 0493.42032)] obtained factorization theorems for \(H^ p(R^ n)\) by singular integral operators. Recently \textit{S. Chanillo} [Indiana Univ. Math. J.
openaire   +4 more sources

Vertex Sparsifiers: New Results from Old Techniques [PDF]

, 2014
Given a capacitated graph $G = (V,E)$ and a set of terminals $K \subseteq V$, how should we produce a graph $H$ only on the terminals $K$ so that every (multicommodity) flow between the terminals in $G$ could be supported in $H$ with low congestion, and ...
Andoni A., Anupam Gupta, Archer A., Calinescu G., Chekuri C., Chuzhoy J., Fakcharoenphol J., Fakcharoenphol J., Golovin D., Gupta A., Harald Räcke, Hoory S., Hubert Chan T.-H., Inbal Talgam-Cohen, Kamma L., Klein P., Kunal Talwar, Lee J. R., Lee J. R., Leighton T., Leighton T., Matthias Englert, Rao S., Räcke H., Robert Krauthgamer   +24 more
core   +3 more sources

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

Population Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source