Results 61 to 70 of about 36,099,759 (329)

Coprime Factor Reduction of H-infinity Controllers [PDF]

, 2003
We consider the efficient solution of the coprime factorization based H infinity controller approximation problems by using frequency-weighted balancing related model reduction approaches.
Varga, Andras
core  

Vertex Sparsifiers: New Results from Old Techniques [PDF]

, 2014
Given a capacitated graph $G = (V,E)$ and a set of terminals $K \subseteq V$, how should we produce a graph $H$ only on the terminals $K$ so that every (multicommodity) flow between the terminals in $G$ could be supported in $H$ with low congestion, and ...
Andoni A., Anupam Gupta, Archer A., Calinescu G., Chekuri C., Chuzhoy J., Fakcharoenphol J., Fakcharoenphol J., Golovin D., Gupta A., Harald Räcke, Hoory S., Hubert Chan T.-H., Inbal Talgam-Cohen, Kamma L., Klein P., Kunal Talwar, Lee J. R., Lee J. R., Leighton T., Leighton T., Matthias Englert, Rao S., Räcke H., Robert Krauthgamer   +24 more
core   +3 more sources

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma

Frontiers in Immunology, 2017
The complement factor H-related (FHR) proteins are hypothesized to fine-tune the regulatory role of complement factor H (FH) in the alternative pathway of the complement system.
Anna E. van Beek, Anna E. van Beek, Richard B. Pouw, Richard B. Pouw, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Pleuni Ooijevaar-de Heer, Martin de Boer, Karin van Leeuwen, Theo Rispens, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers   +13 more
doaj   +1 more source

Tuning the Functionality by Splicing: Factor H and Its Alternative Splice Variant FHL-1 Share a Gene but Not All Functions

Frontiers in Immunology, 2020
The alternative pathway regulator Factor H-like protein 1 (FHL-1) is composed of the first 7 N-terminal complement control protein domains of Factor H (FH) and protects host surfaces from uncontrolled complement attack.
Marco Mannes, Arthur Dopler, Markus Huber-Lang, Christoph Q. Schmidt   +3 more
doaj   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

Population Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.

Journal of Clinical Investigation, 2014
The renal disorder C3 glomerulopathy with dense deposit disease (C3G-DDD) pattern results from complement dysfunction and primarily affects children and young adults. There is no effective treatment, and patients often progress to end-stage renal failure.
Qiang Chen, M. Wiesener, H. Eberhardt, A. Hartmann, B. Uzonyi, M. Kirschfink, K. Amann, M. Buettner, T. Goodship, C. Hugo, C. Skerka, P. Zipfel   +11 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source