Results 91 to 100 of about 14,184,553 (374)

The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men [PDF]

, 2003
Light to moderate drinking is associated with lower risk of coronary heart (CHD) than non-drinkers. We have examined the relationships between total alcohol intake and type of alcoholic beverage and several potential biological mechanisms. We carried out
Lennon, L., Lowe, G.D.O., Rumley, A., Shaper, G., Walker, M., Wannamethee, S.G., Whincup, P.H.   +6 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Weak proton capture on 3He [PDF]

, 2000
The astrophysical S-factor for the proton weak capture on 3He is calculated with correlated-hyperspherical-harmonics bound and continuum wave functions corresponding to realistic Hamiltonians consisting of the Argonne v14 or Argonne v18 two-nucleon and ...
Beacom, J. F., Kievsky, A., Marcucci, L. E., Rosati, S., Schiavilla, R., Viviani, M.   +5 more
core   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer.

Blood, 2012
In previous work we transferred a human factor IX-encoding adeno-associated viral vector (AAV) into skeletal muscle of men with severe hemophilia B.
G. Buchlis, G. Podsakoff, A. Radu, S. Hawk, A. Flake, F. Mingozzi, K. High   +6 more
semanticscholar   +1 more source

F9 Malmö, factor IX and deep vein thrombosis

Haematologica, 2009
Background We recently reported the association between the Malmö sequence variant in F9 (rs6048) and deep vein thrombosis.Design and Methods We aimed to study whether the association between F9 Malmö and deep vein thrombosis is explained by linkage ...
Irene D. Bezemer, Andre R. Arellano, Carmen H. Tong, Charles M. Rowland, Helen A. Ireland, Kenneth A. Bauer, Joseph Catanese, Pieter H. Reitsma, Carine J.M. Doggen, James J. Devlin, Frits R. Rosendaal, Lance A. Bare   +11 more
doaj   +1 more source

CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs

Haematologica, 2020
Hemophilia B is an X-linked recessive bleeding disorder caused by abnormalities in the coagulation factor IX gene. Without prophylactic treatment, patients experience frequent spontaneous bleeding episodes.
Jiahuan Chen, Beiying An, Biao Yu, Xiaohuan Peng, Hongming Yuan, Qiangbing Yang, Xue Chen, Tingting Yu, Lingyu Wang, Xinwei Zhang, He Wang, Xiaodong Zou, Daxin Pang, Hongsheng Ouyang, Xiaochun Tang   +14 more
doaj   +1 more source

CHIANTI - An atomic database for emission lines. XI. EUV emission lines of Fe VII, Fe VIII and Fe IX observed by Hinode/EIS [PDF]

, 2009
A detailed study of emission lines from Fe VII, Fe VIII and Fe IX observed by the EUV Imaging Spectrometer on board the Hinode satellite is presented. Spectra in the ranges 170-212 A and 246-292 A show strongly enhanced lines from the upper solar transition region (temperatures 5.4 <= log T <= 5.9) allowing a number of new line identifications to be ...
arxiv   +1 more source

Concurrent acquired inhibitors to factor VIII and IX, a laboratory artifact: a case report. [PDF]

, 2016
Acquired inhibitors to coagulation factors other than factor VIII are extremely rare. We describe a case of a 59-year-old woman with abnormal bleeding, diagnosed with concurrent inhibitor antibodies to factor VIII and IX by Bethesda testing.
Andreas Hillarp, Dušan Andoljšek, Irena Preložnik Zupan, Peter Černelč, Saša Anžej Doma, Tadej Pajič   +5 more
core   +2 more sources

Enhancement of the enzymatic activity of activated coagulation factor IX by anti-factor IX antibodies [PDF]

Journal of Thrombosis and Haemostasis, 2008
Factor VIIIa (FVIIIa) binds to activated FIX and enhances the activation of FX by several orders of magnitude. Deficiency of FVIII causes the bleeding disorder hemophilia A and is treated by i.v. infusion of FVIII concentrates.To explore whether or not FVIII activity can be supplied by alternative molecules, e.g.
Randolf Kerschbaumer, Jan Rosing, F. Scheiflinger, Michael Dockal   +3 more
openaire   +3 more sources